Simultaneous determination of acetaminophen and dopamine using SWCNT modified carbon-ceramic electrode by differential pulse voltammetry

被引:127
作者
Habibi, Biuck [1 ]
Jahanbakhshi, Mojtaba [1 ]
Pournaghi-Azar, Mohammad Hossein [2 ]
机构
[1] Azarbaijan Univ Tarbiat Moallem, Electroanalyt Chem Lab, Dept Chem, Fac Sci, Tabriz, Iran
[2] Univ Tabriz, Electroanalyt Chem Lab, Fac Chem, Tabriz, Iran
关键词
Simultaneous determination; Differential pulse voltammetry; Single wall carbon nanotubes; Acetaminophen; Dopamine; SIMULTANEOUS ELECTROCHEMICAL DETERMINATION; PYROLYTIC-GRAPHITE ELECTRODE; COMPOSITE FILM ELECTRODE; ASCORBIC-ACID; URIC-ACID; SOL-GEL; NANOTUBES; SENSOR; CHEMISTRY;
D O I
10.1016/j.electacta.2010.12.079
中图分类号
O646 [电化学、电解、磁化学];
学科分类号
081704 ;
摘要
A highly sensitive method was investigated for the simultaneous determination of acetaminophen (AC) and dopamine (DA) using single wall carbon nanotubes modified carbon-ceramic electrode (SWCNT/CCE). The SWCNT/CCE displayed excellent electrochemical catalytic activities towards the oxidation of AC and DA. Under optimized experimental conditions in differential pulse voltammetry technique. AC and DA gave linear response over the ranges 0.2-100.0 mu M (R-2 = 0.996) and 0.4-150.0 mu M (R-2 = 0.999), respectively. The detection limits (S/N = 3) were found to be 0.12 mu M for AC and 0.22 mu M for DA. The present method was applied to the determination of AC and DA in some commercial pharmaceutical samples. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2888 / 2894
页数:7
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