Defibrillation via the elimination of spiral turbulence in a model for ventricular fibrillation

被引:99
作者
Sinha, S [1 ]
Pande, A
Pandit, R
机构
[1] Indian Inst Sci, Dept Phys, Ctr Condensed Matter Theory, Bangalore 560012, Karnataka, India
[2] Jawaharlal Nehru Ctr Adv Sci Res, Condensed Matter Theory Unit, Bangalore 560064, Karnataka, India
关键词
D O I
10.1103/PhysRevLett.86.3678
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
Ventricular fibrillation, the major reason behind sudden cardiac death, is turbulent cardiac electrical activity in which rapid, irregular disturbances in the spatiotemporal electrical activation of the heart make it incapable of any concerted pumping action. Methods of controlling ventricular fibrillation include electrical defibrillation as well as injected medication. Electrical defibrillation, though widely used, involves subjecting the whole heart to massive, and often counterproductive, electrical shocks. We propose a defibrillation method that uses a very low-amplitude shock (of order mV) applied for a brief duration (of order 100 ms) and over a coarse mesh of lines on our model ventricle.
引用
收藏
页码:3678 / 3681
页数:4
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