Biocompatible and photocrosslinkable poly(ethylene glycol)/keratin biocomposite hydrogels

被引：10
作者：
Wang, Chenshu [1 ]
Wang, Lijuan [1 ]
Wan, Xiuzhen [1 ]
Jiang, Xuefeng [1 ]
Yuan, Jiang [1 ]
机构：
[1] Nanjing Normal Univ, Jiangsu Collaborat Innovat Ctr Biomed Funct Mat, Jiangsu Key Lab Biofunct Mat, Sch Chem & Mat Sci, Nanjing 210023, Peoples R China
来源：
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION | 2021年 / 32卷 / 15期
关键词：
Methacrylated keratin; hydrogel; photocrosslinking; PEGDMA; biocompatibility; HUMAN HAIR; KERATIN; BIOMATERIALS;
D O I：
10.1080/09205063.2021.1952384
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
A biocompatible hydrogel is ideal for tissue engineering and regeneration. In this study, methacrylated keratin (KerMA) was synthesized for the first time and then blended with poly(ethylene glycol dimethacrylate) (PEGDMA) to form hydrogel through photocrosslinking. The chemical structure, gelation time, swelling behavior, hydrophilicity, cytotoxicity, and 3D printability of PEGDMA/KerMA hydrogels were characterized and exploited. The PEGDMA/KerMA hydrogels performed good cytocompatibility, providing potential applications for tissue engineering and regenerative medicine.
引用
收藏
页码：1998 / 2008
页数：11
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