Two dimensional population balance modelling of crystal growth behaviour under the influence of impurities

被引:13
作者
Zhang, Yang [1 ]
Liu, Jing Jing [1 ]
Wan, Jian [1 ]
Wang, Xue Z. [1 ,2 ]
机构
[1] S China Univ Technol, Sch Chem & Chem Engn, Guangzhou 510641, Guangdong, Peoples R China
[2] Univ Leeds, Sch Chem & Proc Engn, Inst Particle Sci & Engn, Leeds LS2 9JT, W Yorkshire, England
基金
英国工程与自然科学研究理事会;
关键词
Impurity; Additives; Crystal shape distribution control; Morphological population balance; L-Glutamic acid; L-GLUTAMIC ACID; TAILOR-MADE ADDITIVES; IMAGE-ANALYSIS; CRYSTALLIZATION PROCESSES; INDUSTRIAL CRYSTALLIZATION; COOLING CRYSTALLIZATION; MOLECULAR-CRYSTALS; PARTICLE-SHAPE; HABIT MODIFICATION; MORPHOLOGY;
D O I
10.1016/j.apt.2015.01.001
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
This short communication investigates the impact of impurity on crystal growth behaviour in terms of crystal shape distribution. A two dimensional population balance model is applied to study the crystal shape changing behaviour in cooling crystallisation producing beta-form L-glutamic acid crystals, in the presence and without the presence of an additive, L-phenylalanine. The simulation results were verified in experiments using a 1-litre crystalliser for crystallisation of L-glutamic acid. (C) 2015 The Society of Powder Technology Japan. Published by Elsevier B.V. and The Society of Powder Technology Japan. All rights reserved.
引用
收藏
页码:672 / 678
页数:7
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