Stereospecific ligands and their complexes. V. Synthesis, characterization and antimicrobial activity of palladium(II) complexes with some alkyl esters of (S,S)-ethylenediamine-N,N′-di-2-propanoic acid

被引:27
|
作者
Vasic, Gordana P. [1 ]
Glodjovic, Verica V. [1 ]
Radojevic, Ivana D. [2 ]
Stefanovic, Olgica D. [2 ]
Comic, Ljiljana R. [2 ]
Djinovic, Vesna M. [3 ]
Trifunovic, Srecko R. [1 ]
机构
[1] Univ Kragujevac, Fac Sci, Dept Chem, Kragujevac 34000, Serbia
[2] Univ Kragujevac, Fac Sci, Dept Biol & Ecol, Kragujevac 34000, Serbia
[3] Univ Belgrade, Fac Chem, Belgrade 11000, Serbia
关键词
Palladium(II) complexes; (S; S)-ethylenediamine-N; N '-di-2-propanoic acid; Antimicrobial activity; VITRO ANTITUMORAL ACTIVITY; PLATINUM(II) COMPLEXES; CRYSTAL-STRUCTURE; SUSCEPTIBILITY; SERIES;
D O I
10.1016/j.ica.2010.05.046
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Three new ligands and their palladium(II) complexes of general formula [PdCl(2)(R(2)-S, S-eddp)] (R = n-propyl, n-butyl and n-pentyl) have been synthesized and characterized by microanalysis, infrared and (1)H and (13)C NMR spectroscopy. Antimicrobial activity of these ligands and complexes was tested by microdilution method and both minimal inhibitory and microbicidal concentration were determined. These tested complexes demonstrated the significant antifungal activity against pathogenic fungi Aspergillus flavus and Aspergillus fumigatus. On the other hand, these complexes demonstrated moderate antibacterial activity. (C) 2010 Published by Elsevier B.V.
引用
收藏
页码:3606 / 3610
页数:5
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