Dowling-Degos Disease: Case Report and Review of the Literature

被引：12

作者：

Batycka-Baran, Aleksandra ^{[1
]}

Baran, Wojciech ^{[1
]}

Hryncewicz-Gwozdz, Anita ^{[1
]}

Burgdorf, Walter ^{[2
]}

机构：

[1] Wroclaw Med Univ, Dept Dermatol Venereol & Allergol, PL-50368 Wroclaw, Poland

[2] Univ Munich, Dept Dermatol, D-8000 Munich, Germany

来源：

DERMATOLOGY | 2010年 / 220卷 / 03期

关键词：

Reticulate pigmentation; Axillary and inguinal pigmentations; Dowling-Degos disease; GALLI-GALLI-DISEASE; ACANTHOLYTIC VARIANT; ACQUIRED AXILLARY; MUTATIONS; PIGMENTATION; FLEXURES; SPECTRUM; GENE;

D O I：

10.1159/000278349

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Dowling-Degos disease (DDD) is an unusual pigmentary disorder usually caused by mutations in keratin 5. A 44-year-old woman in good general health presented due to the recent appearance of numerous pigmented macules on her axillary and anogenital skin. A biopsy showed lacy, finger-like epidermal extensions into the dermis which were heavily pigmented and associated with tiny cysts or dilated follicles. We view DDD as part of a spectrum of disorders which are morphologically related but vary in location and time of expression. In addition, both the clinical and histological differential diagnostic considerations are extensive. Copyright (C) 2010 S. Karger AG, Basel

引用

页码：254 / 258

页数：5

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