Recent Advances in the Applications of Triethylsilane in Organic Synthesis

被引:5
作者
Rucilova, Veronika [1 ]
Soural, Miroslav [2 ]
机构
[1] Palacky Univ, Dept Organ Chem, Fac Sci, 17 Listopadu 12, Olomouc 77146, Czech Republic
[2] Palacky Univ, Inst Mol & Translat Med, Fac Med & Dent, Hnevotinska 5, Olomouc 77900, Czech Republic
来源
SYNTHESIS-STUTTGART | 2018年 / 50卷 / 19期
关键词
triethylsilane; reduction; reductive coupling; reductive cyclization; heterocycles; STEREOSELECTIVE-SYNTHESIS; CHEMOSELECTIVE REDUCTION; SELECTIVE REDUCTION; CATALYZED REDUCTION; ENANTIOSELECTIVE SYNTHESIS; UNACTIVATED ALKYNES; CARBONYL-COMPOUNDS; CARBOXYLIC-ACIDS; AROMATIC-AMINES; N-HETEROCYCLES;
D O I
10.1055/s-0037-1610107
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis of pharmacologically relevant scaffolds is an important goal in modern organic chemistry. For this reason, the use of methodologies involving operationally simple procedures and easily handled reagents to chemoselectively and stereoselectively convert different functionalities has gained considerable attention. In this review, we summarize the latest trends in reductive reactions using triethylsilane as the key reagent that provide synthetically interesting intermediates, coupling products and structures with control of the 3D architecture.
引用
收藏
页码:3809 / 3824
页数:16
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