Fine needle aspiration cytology and immunocytochemistry in tuberculosis thyroiditis - A case report

被引:4
作者
Goel, Madhu Mati [1 ]
Budhwar, Puja [1 ]
机构
[1] King Georges Med Univ, Dept Pathol, Lucknow, Uttar Pradesh, India
关键词
aspiration cytology; fine-needle; granulomatous inflammation; immunocytochemistry; thyroid; thyroiditis; tuberculosis;
D O I
10.1159/000325605
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Background Tuberculosis of the thyroid is very rare and does not strike the clinician as a first clinical diagnosis of a thyroid nodule. To our knowledge, only 40 cases of tuberculous thyroiditis diagnosed by fine needle aspiration cytology (FNAC) are described in the English literature. Case We report a case of tuberculosis thyroiditis in a young woman who presented with a right-side solitary thyroid nodule of short duration (15 days), diagnosed by FNAC and confirmed by positive immunocytochemistry with monoclonal antibody to Mycobacterium tuberculosis complex. Ziehl Neelsen staining for acid-fast bacilli (AFB) was negative. Conclusion FNAC provides a confident preoperative diagnosis of thyroid tuberculosis, obviating the need for unnecessary surgical removal of thyroid nodule. Immunocytochemistry is an important diagnostic adjunct to FNAC in AFB-negative cases.
引用
收藏
页码:602 / 606
页数:5
相关论文
共 26 条
[1]  
Asayama I, 2004, MED SCI MONITOR, V10, pCS37
[2]   IMMUNOHISTOLOGIC ANALYSIS OF MYCOBACTERIAL ANTIGENS BY MONOCLONAL-ANTIBODIES IN TUBERCULOSIS AND MYCOBACTERIOSIS [J].
BARBOLINI, G ;
BISETTI, A ;
COLIZZI, V ;
DAMIANI, G ;
MIGALDI, M ;
VISMARA, D .
HUMAN PATHOLOGY, 1989, 20 (11) :1078-1083
[3]  
BARNES P, 1979, BRIT J DIS CHEST, V73, P187, DOI 10.1016/0007-0971(79)90033-0
[4]   Tuberculosis of the thyroid gland: Review of the literature [J].
Bulbuloglu, E ;
Ciralik, H ;
Okur, E ;
Ozdemir, G ;
Ezberci, F ;
Cetinkaya, A .
WORLD JOURNAL OF SURGERY, 2006, 30 (02) :149-155
[5]   Tuberculosis of the thyroid [J].
Chintamani ;
Sharma, RD ;
Mittal, MK ;
Gupta, K ;
Sinha, AN .
TROPICAL DOCTOR, 2004, 34 (01) :52-53
[6]  
Crompton G K, 1969, Tubercle, V50, P61, DOI 10.1016/0041-3879(69)90008-7
[7]  
DAS DK, 1992, ACTA CYTOL, V36, P517
[8]  
Garg S K, 1987, Indian J Chest Dis Allied Sci, V29, P52
[9]   Nucleic acid amplification of Mycobacterium tuberculosis complex DNA from archival fine needle aspiration smear scrapings vs. fresh fine needle aspirates of tuberculous lymphadenitis [J].
Goel, Madhu Mati ;
Budhwar, Puja ;
Goel, Megha ;
Tiwari, Vandana ;
Jain, Amita .
ACTA CYTOLOGICA, 2006, 50 (04) :393-397
[10]   Polymerase chain reaction vs. conventional diagnosis in fine needle aspirates of tuberculous lymph nodes [J].
Goel, MM ;
Ranjan, V ;
Dhole, TN ;
Srivastava, AN ;
Mehrotra, A ;
Kushwaha, MRS ;
Jain, A .
ACTA CYTOLOGICA, 2001, 45 (03) :333-340