Effect of internal mammary vessels radiation dose on outcomes of free flap breast reconstruction

被引:7
作者
Kaidar-Person, Orit [1 ,2 ,3 ]
Eblan, Michael J. [1 ,2 ]
Caster, Joseph M. [1 ,2 ]
Shah, Amita R. [4 ]
Fried, David [1 ]
Marks, Lawrence B. [1 ,2 ]
Lee, Clara N. [5 ]
Jones, Ellen L. [1 ,2 ]
机构
[1] Univ N Carolina, Dept Radiat Oncol, Chapel Hill, NC 27515 USA
[2] UNC Lineberger Comprehens Canc Ctr, Chapel Hill, NC USA
[3] Rambam Med Ctr, Oncol Inst, Radiat Oncol Unit, Haifa, Israel
[4] Univ Texas Hlth Sci Ctr San Antonio, Div Plast & Reconstruct Surg, San Antonio, TX 78229 USA
[5] Ohio State Univ, Coll Med, Coll Publ Hlth, Dept Plast Surg,Div Hlth Serv Management & Policy, Columbus, OH 43210 USA
关键词
breast cancer; complications; dose; flap; internal mammary vessels; radiation therapy; reconstruction; THERAPY; RADIOTHERAPY; TRENDS;
D O I
10.1111/tbj.13202
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
To assess the impact of internal mammary (IM) vessels radiation dose on autologous free-flap based breast reconstruction outcomes. We retrospectively evaluated the medical records of breast cancer patients who underwent mastectomy and free-flap breast reconstruction after postoperative radiation therapy (RT) to the breast/chest wall with (n = 9) or without (n = 11) electively including the IM lymph nodes. Twenty patients were included. Median age at diagnosis was 50 years (range, 33-63). The median time interval between the start of RT and reconstructive surgery was 16 months (range, 6-45). The maximal IM vessels dose was not associated with the risk of all complications (P = 0.44) or fat necrosis (P = 0.31). The mean IM vessels dose was not significant for the risk of all complications (P = 0.13) but was significant for fat necrosis (P = 0.04). A high mean IM vessels dose was related to the occurrence of fat necrosis.
引用
收藏
页码:286 / 289
页数:4
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