Effect of internal mammary vessels radiation dose on outcomes of free flap breast reconstruction

被引：7

作者：

Kaidar-Person, Orit ^{[1
,2
,3
]}

Eblan, Michael J. ^{[1
,2
]}

Caster, Joseph M. ^{[1
,2
]}

Shah, Amita R. ^{[4
]}

Fried, David ^{[1
]}

Marks, Lawrence B. ^{[1
,2
]}

Lee, Clara N. ^{[5
]}

Jones, Ellen L. ^{[1
,2
]}

机构：

[1] Univ N Carolina, Dept Radiat Oncol, Chapel Hill, NC 27515 USA

[2] UNC Lineberger Comprehens Canc Ctr, Chapel Hill, NC USA

[3] Rambam Med Ctr, Oncol Inst, Radiat Oncol Unit, Haifa, Israel

[4] Univ Texas Hlth Sci Ctr San Antonio, Div Plast & Reconstruct Surg, San Antonio, TX 78229 USA

[5] Ohio State Univ, Coll Med, Coll Publ Hlth, Dept Plast Surg,Div Hlth Serv Management & Policy, Columbus, OH 43210 USA

来源：

BREAST JOURNAL | 2019年 / 25卷 / 02期

关键词：

breast cancer; complications; dose; flap; internal mammary vessels; radiation therapy; reconstruction; THERAPY; RADIOTHERAPY; TRENDS;

D O I：

10.1111/tbj.13202

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

To assess the impact of internal mammary (IM) vessels radiation dose on autologous free-flap based breast reconstruction outcomes. We retrospectively evaluated the medical records of breast cancer patients who underwent mastectomy and free-flap breast reconstruction after postoperative radiation therapy (RT) to the breast/chest wall with (n = 9) or without (n = 11) electively including the IM lymph nodes. Twenty patients were included. Median age at diagnosis was 50 years (range, 33-63). The median time interval between the start of RT and reconstructive surgery was 16 months (range, 6-45). The maximal IM vessels dose was not associated with the risk of all complications (P = 0.44) or fat necrosis (P = 0.31). The mean IM vessels dose was not significant for the risk of all complications (P = 0.13) but was significant for fat necrosis (P = 0.04). A high mean IM vessels dose was related to the occurrence of fat necrosis.

引用

页码：286 / 289

页数：4

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