A pH-responsive drug delivery system with an aggregation-induced emission feature for cell imaging and intracellular drug delivery

被引：89
作者：
Wang, Haibo [1 ]
Liu, Gongyan [2 ,3 ]
Gao, Haiqi [2 ]
Wang, Yunbing [3 ]
机构：
[1] Sichuan Univ, Coll Light Ind Text & Food Engn, Text Inst, Chengdu 610065, Peoples R China
[2] Sichuan Univ, Natl Engn Lab Clean Technol Leather Manufacture, Chengdu 610065, Peoples R China
[3] Sichuan Univ, Natl Engn Res Ctr Biomat, Chengdu 610065, Peoples R China
来源：
POLYMER CHEMISTRY | 2015年 / 6卷 / 26期
关键词：
MESOPOROUS SILICA NANOPARTICLES; FACILE PREPARATION; CANCER-THERAPY; MICELLES; EMITTERS; PRODRUG; TUMORS;
D O I：
10.1039/c5py00584a
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
A pH-responsive fluorescent vehicle based on aggregation-induced emission (AIE) has been developed as a drug delivery system, which could be traced in cancer cells and further exhibited high cytotoxicity in tumor cells due to its excellent sensitivity at the endosomal pH.
引用
收藏
页码：4715 / 4718
页数：4
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