Urinary tract infections in cystic fibrosis patients

被引：0

作者：

Reasoner, Seth A. ^{[1
]}

Enriquez, Kyle T. ^{[2
]}

Abelson, Benjamin ^{[3
]}

Scaglione, Steven ^{[2
]}

Schneier, Bennett ^{[1
]}

O'Connor, Michael G. ^{[4
]}

Van Horn, Gerald ^{[1
,5
]}

Hadjifrangiskou, Maria ^{[1
,5
,6
]}

机构：

[1] Vanderbilt Univ, Med Ctr, Dept Pathol Microbiol & Immunol, Div Mol Pathogenesis, Nashville, TN 37235 USA

[2] Vanderbilt Univ, Sch Med, Nashville, TN 37212 USA

[3] Vanderbilt Univ, Med Ctr, Dept Urol, Div Pediat Urol, Nashville, TN USA

[4] Vanderbilt Univ, Med Ctr, Dept Pediat, Div Pediat Pulm Allergy & Immunol, Nashville, TN 37232 USA

[5] Vanderbilt Univ, Med Ctr, Ctr Personalized Microbiol CPMi, Nashville, TN 37235 USA

[6] Vanderbilt Univ, Med Ctr, Vanderbilt Inst Infect Immunol & Inflammat VI4, Nashville, TN 37235 USA

来源：

JOURNAL OF CYSTIC FIBROSIS | 2022年 / 21卷 / 01期

关键词：

Cystic fibrosis; Urinary tract infection; Antibiotic resistance; Cystitis; COMORBIDITIES;

D O I：

10.1016/j.jcf.2021.07.005

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Improved understanding of non-respiratory infections in cystic fibrosis (CF) patients will be vital to sustaining the increased life span of these patients. To date, there has not been a published report of urinary tract infections (UTIs) in CF patients. We performed a retrospective chart review at a major academic medical center during 2010-2020 to determine the features of UTIs in 826 CF patients. We identified 108 UTI episodes during this period. Diabetes, distal intestinal obstruction syndrome (DIOS), and nephrolithiasis were correlated with increased risk of UTIs. UTIs in CF patients were less likely to be caused by Gram-negative rods compared to non-CF patients and more likely to be caused by Enterococcus faecalis . The unique features of UTIs in CF patients highlight the importance of investigating non-respiratory infections to ensure appropriate treatment. (c) 2021 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.

引用

页码：E1 / E4

页数：4

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