Polycyclic N-Heterocyclic Compounds, Part 69: Synthesis of 5-amino-1,2-dihydro[1]benzofuro[3,2-d]furo[2,3-b]pyridines and their transformations to related compounds

被引：8

作者：

Okuda, Kensuke ^{[1
]}

Takano, Jun-ichi ^{[2
]}

Hirota, Takashi ^{[2
]}

Sasaki, Kenji ^{[2
]}

机构：

[1] Gifu Pharmaceut Univ, Lab Med & Pharmaceut Chem, Gifu 5011196, Japan

[2] Okayama Univ, Fac Pharmaceut Sci, Lab Pharmaceut Chem, Kita Ku, Okayama 7008530, Japan

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2012年 / 49卷 / 02期

关键词：

TRUCE-SMILES REARRANGEMENT; DERIVATIVES;

D O I：

10.1002/jhet.772

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of 3-(3-cyanopropoxy)[1]benzofuran-2-carbonitriles with potassium tert-butoxide gave 5-amino-1,2-dihydro[1]benzofuro[3,2-d]furo[2,3-b]pyridines and 5-amino-2,3-dihydro[1]benzofuro[3,2-b]oxepin-4-carbonitriles as new ring systems. Reactions of the 5-chloro derivative, obtained from 5-amino-1,2-dihydro[1]benzofuro[3,2-d]furo[2,3-b]pyridine, produced a dihydrofuran ring-opened compound and 5-substituted compounds. J. Heterocyclic Chem.,(2011).

引用

页码：281 / 287

页数：7

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