New camphor-derived selenonium ylides: Enantioselective synthesis of chiral epoxides

被引：9

作者：

Li, XL ^{[1
]}

Wang, Y ^{[1
]}

Huang, ZZ ^{[1
]}

机构：

[1] Nanjing Univ, Sch Chem & Chem Engn, Nanjing 210093, Peoples R China

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 2005年 / 58卷 / 10期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1071/CH05157

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Optically pure selenonium salts 3 as the precursors of two new chiral selenonium ylides 4 can be synthesized stereoselectively from natural D-camphor in good yields. It is found that the reaction of the selenonium salt 3b, an aldehyde, and potassium tert-butoxide can take place smoothly in 'one-pot' via the formation of selenonium ylide 4b, to give chiral trans-diaryl epoxides 5 in good yields with good diastereoselectivities and enantioselectivities.

引用

页码：749 / 752

页数：4

共 24 条

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