Gold nanorods-silica Janus nanoparticles for theranostics

被引：46

作者：

Wang, Ying-Shuai ^{[1
]}

Shao, Dan ^{[2
]}

Zhang, Lu ^{[1
]}

Zhang, Xu-Lin ^{[1
]}

Li, Jing ^{[2
]}

Feng, Jing ^{[1
]}

Xia, Hong ^{[1
]}

Huo, Qi-Sheng ^{[3
]}

Dong, Wen-Fei ^{[1
]}

Sun, Hong-Bo ^{[1
]}

机构：

[1] Jilin Univ, Coll Elect Sci & Engn, State Key Lab Integrated Optoelect, Changchun 130012, Peoples R China

[2] Jilin Univ, Coll Basic Med Sci, Dept Pharmacol, Changchun 130021, Peoples R China

[3] Jilin Univ, Coll Chem, State Key Lab Inorgan Synth & Preparat Chem, Changchun 130012, Peoples R China

来源：

APPLIED PHYSICS LETTERS | 2015年 / 106卷 / 17期

基金：

中国国家自然科学基金;

关键词：

OPTICAL-PROPERTIES; DELIVERY; PLATFORM; CELLS; SIZE; SEED;

D O I：

10.1063/1.4919454

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

A multi-functional gold nanorods-mesoporous silica Janus nanoparticles (NPs) were fabricated by a facile and mild strategy. These Janus NPs not only exhibit small shift of the local surface plasmon resonance wavelength but also have high potential for drug loading and low cytotoxicity. More importantly, the Janus nano-composites could efficiently deliver the imaging agents or drugs into liver cancer cells, at the same time the Janus NPs have good effect on photothermal, which indicate that the unique Janus NPs could be a promising candidate of theranostic system for combined photothermo-/chemo-cancer therapy. (C) 2015 AIP Publishing LLC.

引用

页数：4

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