Chiral polyethers derived from BINOL and ECH as highly enantioselective and efficient catalysts for the borane reduction of prochiral ketones

被引：11

作者：

Zhang, An-Lin ^{[1
]}

Yu, Zeng-da ^{[1
]}

Yang, Li-Wen ^{[1
]}

Yang, Nian-Fa ^{[1
]}

Peng, Dan ^{[1
]}

机构：

[1] Xiangtan Univ, Coll Chem, Minist Educ, Key Lab Environm Friendly Chem & Applicat, Xiangtan 411105, Hunan, Peoples R China

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2015年 / 398卷

基金：

美国国家科学基金会; 高等学校博士学科点专项科研基金;

关键词：

Polyether; BINOL; Epichlorohydrin; Reduction; Enantioselectivity; TRANSITION-METAL-COMPLEXES; DIOL TRIDENTATE LIGANDS; ASYMMETRIC REDUCTION; RECOVERABLE CATALYSTS; DERIVATIVES; ALDEHYDES; ACID; IMMOBILIZATION; METHYLLITHIUM; DIETHYLZINC;

D O I：

10.1016/j.molcata.2015.01.007

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Two novel polyethers derived from BINOL were synthesized and used to induce the enantioselective borane reduction of prochiral ketones. The polyethers gave the expected secondary alcohols with up to 98% yields and over 99% ee values. The recovered polyethers could be reused for many times to induce the enantioselective reduction of prochiral ketones without losing their enantioselective induction ability. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：407 / 412

页数：6

共 59 条

[1] Polymer-supported L-prolinol-based catalysts for the enantioselective addition of dialkylzinc reagents to N-(diphenylphosphinyl)imines [J].