One-pot three component reaction involving cyclohexyl isocyanide for the synthesis of furo[3,4-b]chromenes

被引：14

作者：

Panja, Suman Kalyan ^{[1
]}

Maiti, Sourav ^{[1
]}

Drew, Michael G. B. ^{[2
]}

Bandyopadhyay, Chandrakanta ^{[1
]}

机构：

[1] RK Mission Vivekananda Centenary Coll, Dept Chem, Kolkata 700118, W Bengal, India

[2] Univ Reading, Dept Chem, Reading RG6 6AD, Berks, England

来源：

JOURNAL OF CHEMICAL RESEARCH | 2011年 / 04期

关键词：

3-formylchromone; multicomponent reaction; isocyanide; furo[3,4-b]chromene; atom economy; chromene;

D O I：

10.3184/174751911X13015945166625

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

On stirring an equimolar mixture of 4-oxo-4H-chromene-3-carbaldehyde, ninhydrin and cyclohexyl isocyanide in CH2Cl2-MeOH (7: 1) at room temperature produces 3-cyclohexylimino-1-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)-1,3-dihydro-9H-furo[3,4-b]chromen-9-one which on hydrolysis produces 1-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)-1H-furo[3,4-b]chromene-3,9-dione. The structure of the latter compound was confirmed by single crystal X-ray diffraction.

引用

页码：225 / 228

页数：4

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