Pediatric intestinal transplantation

被引：5

作者：

Soltys, Kyle A. ^{[1
]}

Bond, Geoff ^{[1
]}

Sindhi, Rakesh ^{[1
]}

Rassmussen, Sara K. ^{[2
]}

Ganoza, Armando ^{[1
]}

Khanna, Ajai ^{[1
]}

Mazariegos, George ^{[1
]}

机构：

[1] Univ Pittsburgh, Childrens Hosp Pittsburgh, Hillman Ctr Pediat Transplantat, Med Ctr, 4401 Penn Ave,6 FP, Pittsburgh, PA 15224 USA

[2] Univ Virginia, Dept Surg, Charlottesville, VA USA

来源：

SEMINARS IN PEDIATRIC SURGERY | 2017年 / 26卷 / 04期

关键词：

Intestinal failure; Intestinal transplant; Immunosuppression; Infection; Post-transplant lymphoproliferative disease; Quality of life; SMALL-BOWEL TRANSPLANTATION; QUALITY-OF-LIFE; POSTTRANSPLANT LYMPHOPROLIFERATIVE DISEASE; MICROVILLOUS INCLUSION DISEASE; SEVERE COMBINED IMMUNODEFICIENCY; MULTIVISCERAL TRANSPLANTATION; HYPOPERISTALSIS SYNDROME; INFECTIOUS COMPLICATIONS; MOTILITY DISORDERS; CYTOMEGALOVIRUS DISEASE;

D O I：

10.1053/j.sempedsurg.2017.07.007

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The field of intestinal transplantation has experienced dramatic growth since the first reported cases 3 decades ago. Improvements in operative technique, donor assessment and immunosuppressive protocols have afforded children who suffer from life-threatening complications of intestinal failure a chance at long-term survival. As experience has grown, newer diseases, with more systemic manifestations have arisen as potential indications for transplant. After discussing the historical developments of intestinal transplant as a backdrop, this review focuses on the specific pre-operative indications for transplant as well as the great success that intestinal rehabilitation has witnessed over the past decade. A detailed discussion of evolution of immunosuppressive strategies is followed a general review of the common infectious complications experienced by children after intestinal transplant as well as the current long and short-term results, including a section on new research on the quality of life in this challenging population of patients. (c) 2017 Elsevier Inc. All rights reserved.

引用

页码：241 / 249

页数：9

共 77 条

[1]

Abu-Elmagd Kareem M, 2012, Clin Transpl, P155

[2] Long-Term Survival, Nutritional Autonomy, and Quality of Life After Intestinal and Multivisceral Transplantation [J].

Abu-Elmagd, Kareem M. ;

Kosmach-Park, Beverly ;

Costa, Guilherme ;

Zenati, Mazen ;

Martin, Lillian ;

Koritsky, Darlene A. ;

Emerling, Maureen ;

Murase, Noriko ;

Bond, Geoffrey J. ;

Soltys, Kyle ;

Sogawa, Hiroshi ;

Lunz, John ;

Al Samman, Motaz ;

Shaefer, Nico ;

Sindhi, Rakesh ;

Mazariegos, George V. .

ANNALS OF SURGERY, 2012, 256 (03) :494-508

[3] Lymphoproliferative Disorders and De Novo Malignancies in Intestinal and Multivisceral Recipients: Improved Outcomes With New Outlooks [J].

Abu-Elmagd, Kareem M. ;

Mazariegos, George ;

Costa, Guilherme ;

Soltys, Kyle ;

Bond, Geoffrey ;

Sindhi, Rakesh ;

Green, Michael ;

Jaffe, Ronald ;

Wu, Tong ;

Koritsky, Darlene ;

Matarese, Laura ;

Schuster, Bonnie ;

Martin, Lillian ;

Dvorchik, Igor ;

Nalesnik, Michael A. .

TRANSPLANTATION, 2009, 88 (07) :926-934

[4] Five Hundred Intestinal and Multivisceral Transplantations at a Single Center Major Advances With New Challenges [J].

Abu-Elmagd, Kareem M. ;

Costa, Guilherme ;

Bond, Geoffrey J. ;

Soltys, Kyle ;

Sindhi, Rakesh ;

Wu, Tong ;

Koritsky, Darlene A. ;

Schuster, Bonita ;

Martin, Littian ;

Cruz, Ruy J. ;

Murase, Noriko ;

Zeevi, Adriana ;

Irish, William ;

Ayyash, Maher O. ;

Matarese, Laura ;

Humar, Abhinav ;

Mazariegos, George .

ANNALS OF SURGERY, 2009, 250 (04) :567-581

[5] Evolution of the immunosuppressive strategies for the intestinal and multivisceral recipients with special reference to allograft immunity and achievement of partial tolerance [J].

Abu-Elmagd, Kareem M. ;

Costa, Guilherme ;

Bond, Geoffrey J. ;

Wu, Tong ;

Murase, Noriko ;

Zeevi, Adriana ;

Simmons, Richard ;

Soltys, Kyle ;

Sindhi, Rakesh ;

Stein, William ;

Demetris, Anthony ;

Mazariegos, George .

TRANSPLANT INTERNATIONAL, 2009, 22 (01) :96-109

[6] Hirschsprung disease, associated syndromes and genetics: a review [J].

Amiel, J. ;

Sproat-Emison, E. ;

Garcia-Barcelo, M. ;

Lantieri, F. ;

Burzynski, G. ;

Borrego, S. ;

Pelet, A. ;

Arnold, S. ;

Miao, X. ;

Griseri, P. ;

Brooks, A. S. ;

Antinolo, G. ;

de Pontual, L. ;

Clement-Ziza, M. ;

Munnich, A. ;

Kashuk, C. ;

West, K. ;

Wong, K. K-Y ;

Lyonnet, S. ;

Chakravarti, A. ;

Tam, P. K-H ;

Ceccherini, I. ;

Hofstra, R. M. W. ;

Fernandez, R. .

JOURNAL OF MEDICAL GENETICS, 2008, 45 (01) :1-14

[7] Predicting Cellular Rejection With a Cell-Based Assay: Preclinical Evaluation in Children [J].

Ashokkumar, Chethan ;

Soltys, Kyle ;

Mazariegos, George ;

Bond, Geoffrey ;

Higgs, Brandon W. ;

Ningappa, Mylarappa ;

Sun, Qing ;

Brown, Amanda ;

White, Jaimie ;

Levy, Samantha ;

Fazzolare, Tamara ;

Remaley, Lisa ;

Dirling, Katie ;

Harris, Patricia ;

Hartle, Tara ;

Kachmar, Pamela ;

Nicely, Megan ;

O'Toole, Lindsay ;

Boehm, Brittany ;

Jativa, Nicole ;

Stanley, Paula ;

Jaffe, Ronald ;

Ranganathan, Sarangarajan ;

Zeevi, Adriana ;

Sindhi, Rakesh .

TRANSPLANTATION, 2017, 101 (01) :131-140

[8] Enteric Nervous System Impairment in Gastroschisis [J].

Auber, Frederic ;

Danzer, Enrico ;

Noche-Monnery, Marie-Emmanuelle ;

Sarnacki, Sabine ;

Trugnan, Germain ;

Boudjemaa, Sabah ;

Audry, Georges .

EUROPEAN JOURNAL OF PEDIATRIC SURGERY, 2013, 23 (01) :29-38

[9] Small bowel transplantation complicated by cytomegalovirus tissue invasive disease without viremia [J].

Avsar, Yesim ;

Cicinnati, Vito R. ;

Kabar, Iyad ;

Wolters, Heiner ;

Anthoni, Christoph ;

Schmidt, Hartmut H. J. ;

Beckebaum, Susanne .

JOURNAL OF CLINICAL VIROLOGY, 2014, 60 (02) :174-177

[10] Immunologic Challenges in Small Bowel Transplantation [J].

Berger, M. ;

Zeevi, A. ;

Farmer, D. G. ;

Abu-Elmagd, K. M. .

AMERICAN JOURNAL OF TRANSPLANTATION, 2012, 12 :S2-S8

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