Not just a circle: flux modes in the plant TCA cycle

被引：642

作者：

Sweetlove, Lee J. ^{[1
]}

Beard, Katherine F. M. ^{[1
]}

Nunes-Nesi, Adriano ^{[2
]}

Fernie, Alisdair R. ^{[2
]}

Ratcliffe, R. George ^{[1
]}

机构：

[1] Univ Oxford, Dept Plant Sci, Oxford OX1 3RB, England

[2] Max Planck Inst Mol Plant Physiol, D-14476 Potsdam, Germany

来源：

TRENDS IN PLANT SCIENCE | 2010年 / 15卷 / 08期

基金：

英国生物技术与生命科学研究理事会;

关键词：

COMPARTMENTED METABOLIC FLUXES; TRICARBOXYLIC-ACID CYCLE; MITOCHONDRIAL METABOLISM; NITRATE ASSIMILATION; PHOTOSYNTHETIC PERFORMANCE; DEHYDROGENASE-ACTIVITY; ILLUMINATED LEAVES; REDUCED EXPRESSION; ENZYME REDUNDANCY; MILD REDUCTIONS;

D O I：

10.1016/j.tplants.2010.05.006

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The tricarboxylic acid (TCA) cycle is one of the iconic pathways in metabolism. The cycle is commonly thought of in terms of energy metabolism, being responsible for the oxidation of respiratory substrates to drive ATP synthesis. However, the reactions of carboxylic acid metabolism are embedded in a larger metabolic network and the conventional TCA cycle is only one way in which the component reactions can be organised. Recent evidence from labelling studies and metabolic network models suggest that the organisation of carboxylic acid metabolism in plants is highly dependent on the metabolic and physiological demands of the cell. Thus, alternative, non-cyclic flux modes occur in leaves in the light, in some developing oilseeds, and under specific physiological circumstances such as anoxia.

引用

页码：462 / 470

页数：9

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