Automated system for the on-line monitoring of powder blending processes using near-infrared spectroscopy .1. System development and control

被引:113
作者
Hailey, PA
Doherty, P
Tapsell, P
Oliver, T
Aldridge, PK
机构
[1] PFIZER LTD,CENT RES,DISCOVERY HQ,SANDWICH CT13 9NJ,KENT,ENGLAND
[2] PFIZER INC,CENT RES,ANALYT RES & DEV,GROTON,CT 06340
关键词
near-infrared spectroscopy; on-line analysis; fibre-optics; blending; chemometrics; pharmaceutical analysis; process control;
D O I
10.1016/0731-7085(95)01674-0
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
An automated system for the on-line monitoring of powder blending processes is described. The system employs near-infrared (NIR) spectroscopy using fibre-optics and a graphical user interface (GUI) developed in the LabVIEW environment. The complete supervisory control and data analysis (SCADA) software controls blender and spectrophotometer operation and performs statistical spectral data analysis in real time. A data analysis routine using standard deviation is described to demonstrate an approach to the real-time determination of blend homogeneity.
引用
收藏
页码:551 / 559
页数:9
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