Automated system for the on-line monitoring of powder blending processes using near-infrared spectroscopy .1. System development and control

被引:113
|
作者
Hailey, PA
Doherty, P
Tapsell, P
Oliver, T
Aldridge, PK
机构
[1] PFIZER LTD,CENT RES,DISCOVERY HQ,SANDWICH CT13 9NJ,KENT,ENGLAND
[2] PFIZER INC,CENT RES,ANALYT RES & DEV,GROTON,CT 06340
关键词
near-infrared spectroscopy; on-line analysis; fibre-optics; blending; chemometrics; pharmaceutical analysis; process control;
D O I
10.1016/0731-7085(95)01674-0
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
An automated system for the on-line monitoring of powder blending processes is described. The system employs near-infrared (NIR) spectroscopy using fibre-optics and a graphical user interface (GUI) developed in the LabVIEW environment. The complete supervisory control and data analysis (SCADA) software controls blender and spectrophotometer operation and performs statistical spectral data analysis in real time. A data analysis routine using standard deviation is described to demonstrate an approach to the real-time determination of blend homogeneity.
引用
收藏
页码:551 / 559
页数:9
相关论文
共 50 条
  • [1] Automated system for the on-line monitoring of powder blending processes using near-infrared spectroscopy - Part II. Qualitative approaches to blend evaluation
    Sekulic, SS
    Wakeman, J
    Doherty, P
    Hailey, PA
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1998, 17 (08) : 1285 - 1309
  • [2] On-line monitoring of powder blending with near-infrared spectroscopy
    De Maesschalck, R
    Sanchez, FC
    Massart, DL
    Doherty, P
    Hailey, P
    APPLIED SPECTROSCOPY, 1998, 52 (05) : 725 - 731
  • [3] On-Line Monitoring of Enzymatic Degumming of Soybean Oil Using Near-Infrared Spectroscopy
    Tonolini, Margherita
    Wawrzynczyk, Joanna
    Nielsen, Per Munk
    Engelsen, Soren Balling
    APPLIED SPECTROSCOPY, 2023, 77 (12) : 1333 - 1343
  • [4] Practical calibration correction method for the maintenance of an on-line near-infrared monitoring system for molten polymers
    Watari, Masahiro
    Ozaki, Yukihiro
    APPLIED SPECTROSCOPY, 2006, 60 (05) : 529 - 538
  • [5] On-line monitoring of the distillates of a solvent switch process by near-infrared spectroscopy
    Ge, ZH
    Buchanan, B
    Timmermans, J
    De Tora, D
    Ellison, D
    Wyvratt, J
    PROCESS CONTROL AND QUALITY, 1999, 11 (04): : 277 - 287
  • [6] On-line monitoring of the buffer capacity of particleboard furnish by near-infrared spectroscopy
    Andre, N.
    Young, T. M.
    Rials, T. G.
    APPLIED SPECTROSCOPY, 2006, 60 (10) : 1204 - 1209
  • [7] Use of near-infrared spectroscopy for on-line monitoring the quality of prepreg cloth
    Li, Wei
    Huang, Yu Dong
    Chen, Ping
    ADVANCED COMPOSITES LETTERS, 2008, 17 (02) : 41 - 48
  • [8] Application of Near-Infrared Spectroscopy for Monitoring and/or Control of Composting Processes
    Cvetnic, Tea Sokac
    Krog, Korina
    Benkovic, Maja
    Jurina, Tamara
    Valinger, Davor
    Redovnikovic, Ivana Radojcic
    Kljusuric, Jasenka Gajdos
    Tusek, Ana Jurinjak
    APPLIED SCIENCES-BASEL, 2023, 13 (11):
  • [9] On-Line Monitoring of Guizhi Fuling Capsules and Tablets Dissolution Behavior Using Near-Infrared Spectroscopy Combined with Chemometrics
    Dong, Wenliang
    Wang, Xi
    Huang, Zhaobo
    Ye, Cheng
    Wang, Tuanjie
    Zhang, Hongda
    Wang, Zhenzhong
    Li, Wenlong
    JOURNAL OF ANALYSIS AND TESTING, 2025,
  • [10] Fast on-line identification of plastics by near-infrared spectroscopy for use in recycling processes
    Eisenreich, N
    Herz, J
    Kull, H
    Mayer, W
    Rohe, T
    ANTEC '96: PLASTICS - RACING INTO THE FUTURE, VOLS I-III: VOL I: PROCESSING; VOL II: MATERIALS; VOL III: SPACIAL AREAS, 1996, 42 : 3131 - 3135