Prognostic value of D-dimer/fibrinogen ratio on in-hospital outcomes of patients with heart failure and COVID-19

被引：7

作者：

Murat, Selda ^{[1
]}

Murat, Bektas ^{[2
]}

Dural, Muhammet ^{[1
]}

Mert, Gurbet Ozge ^{[1
]}

Cavusoglu, Yuksel ^{[1
]}

机构：

[1] Eskisehir Osmangazi Univ, Med Fac, Dept Cardiol, TR-26040 Eskisehir, Turkey

[2] Eskisehir City Hosp, Dept Cardiol, TR-26080 Eskisehir, Turkey

来源：

BIOMARKERS IN MEDICINE | 2021年 / 15卷 / 16期

关键词：

coronavirus disease; D-dimer; fibrinogen ratio; heart failure; D-DIMER; PULMONARY-EMBOLISM; THROMBOEMBOLISM; GUIDELINES; DIAGNOSIS; ACCURACY;

D O I：

10.2217/bmm-2021-0341

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Aim: In the present study, the relationship between D-dimer/fibrinogen ratio (DFR) and in-hospital outcomes was evaluated in patients with COVID-19 and a diagnosis of heart failure (HF). Materials & methods: In-hospital outcomes were compared in patients with high and low DFR values. Results: With regard to in-hospital outcomes, patients in the third tertile of DFR had a higher rate of mechanical ventilation, cardiogenic shock and death (p < 0.001). The length of ICU stay was longer in the third tertile group (p < 0.001). When evaluated together with infection markers, DFR was found to be an independent predictor of outcomes. Conclusion: DFR can be used as a prognostic marker in patients with COVID-19 with a diagnosis of HF, and perhaps more valuable than other infection markers.

引用

页码：1519 / 1528

页数：10

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