Antifungal polysulphides from Petiveria alliacea L.

被引：52
|
作者：
Benevides, PJC
Young, MCM
Giesbrecht, AM
Roque, NF
Bolzani, VDS
机构：
[1] Univ Estadual Paulista, Inst Quim, BR-14800900 Araraquara, SP, Brazil
[2] Univ Sao Paulo, Inst Quim, BR-05599970 Sao Paulo, Brazil
[3] Inst Bot, Dept Fisiol & Bioquim Plantas, BR-01161970 Sao Paulo, Brazil
来源：
PHYTOCHEMISTRY | 2001年 / 57卷 / 05期
基金：
巴西圣保罗研究基金会;
关键词：
Petiveria alliacea; Phytolacaceae; antifungal polysulphides;
D O I：
10.1016/S0031-9422(01)00079-6
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Bioactivity-directed fractionation of the CH2Cl2/MeOH (2:1, v/v) extract of the roots of Petiveria alliacea, using mutant yeast strains of Saccharomyces cerevisiae and fungi Cladosporium cladosporioides and C. sphaerospermum led to the isolation of dipropyl disulphide (1), dibenzyl sulphide (2), dibenzyl disulphide (3), dibenzyl trisulphide (4), dibenzyl tetrasulphide (5), benzylhydroxymethyl sulphide (6) and di(benzyltrithio) methane (7). Of these, 5-7 are new compounds and this is the first report of the natural occurrence of 2 and 3. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：743 / 747
页数：5
相关论文
共 50 条
  • [1] Antibacterial and antifungal activity of sulfur-containing compounds from Petiveria alliacea L.
    Kim, S
    Kubec, R
    Musah, RA
    JOURNAL OF ETHNOPHARMACOLOGY, 2006, 104 (1-2) : 188 - 192
  • [2] Allelopathic potential of Petiveria alliacea L.
    Pérez-Leal, R
    García-Mateos, MR
    Vásquez-Rojas, TR
    Colinas-León, TC
    AGRONOMY FOR SUSTAINABLE DEVELOPMENT, 2005, 25 (02) : 177 - 182
  • [3] Antimicrobial activity of crude extratcs of Petiveria alliacea L.
    Guedes, Rodrigo C. M.
    Nogueira, Natalia G. P.
    Fusco-Almeida, Ana M.
    Souza, Claudia R. F.
    Oliveira, Wanderley P.
    LATIN AMERICAN JOURNAL OF PHARMACY, 2009, 28 (04): : 520 - 524
  • [4] Volatile constituents from in vitro and ex vitro plants of Petiveria alliacea L.
    Castellar, Aline
    Gagliardi, Rachel F.
    Mansur, Elisabeth
    Bizzo, Humberto R.
    Souza, Andressa M.
    Leitao, Suzana G.
    JOURNAL OF ESSENTIAL OIL RESEARCH, 2014, 26 (01) : 19 - 23
  • [5] Immunomodulatory activities of Petiveria alliacea L
    Williams, LAD
    The, TL
    Gardner, MT
    Fletcher, CK
    Naravane, A
    Gibbs, N
    Fleishhacker, R
    PHYTOTHERAPY RESEARCH, 1997, 11 (03) : 251 - 253
  • [6] Study of antinociceptive effect of isolated fractions from Petiveria alliacea L. (tipi) in mice
    Gomes, PB
    Oliveira, MMD
    Nogueira, CRA
    Noronha, EC
    Carneiro, LMV
    Bezerra, JNS
    Neto, MA
    Vasconcelos, SMM
    Fonteles, MMF
    Viana, GSB
    de Sousa, FCF
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2005, 28 (01) : 42 - 46
  • [7] Toxicological evaluation of an aqueous suspension from leaves and stems of Petiveria alliacea L. (Phytolaccaceae)
    Garcia-Perez, Martha-Estrella
    Alfonso-Castillo, Alfredo
    Fong Lores, Onel
    Batista-Duharte, Alexander
    Lemus-Rodriguez, Zoe
    JOURNAL OF ETHNOPHARMACOLOGY, 2018, 211 : 29 - 37
  • [8] Ethnobotany, phytochemistry and neuropharmacological effects of Petiveria alliacea L. (Phytolaccaceae): A review
    Luz, Diandra Araujo
    Pinheiro, Alana Miranda
    Silva, Mallone Lopes
    Monteiro, Marta Chagas
    Prediger, Rui Daniel
    Ferraz Maia, Cristiane Socorro
    Fontes-Junior, Eneas Andrade
    JOURNAL OF ETHNOPHARMACOLOGY, 2016, 185 : 182 - 201
  • [9] Central effects of isolated fractions from the root of Petiveria alliacea L. (tipi) in mice
    Gomes, Patricia B.
    Noronha, Emmanuelle C.
    de Melo, Carla Thiciane V.
    Bezerra, Jose N. S.
    Neto, Manoel A.
    Lino, Cleide S.
    Vasconcelos, Silvania M. M.
    Viana, Glauce S. B.
    de Sousa, Francisca Clea F.
    JOURNAL OF ETHNOPHARMACOLOGY, 2008, 120 (02) : 209 - 214
  • [10] Acaricidal Activity and Essential Oil Composition of Petiveria alliacea L. from Pernambuco (Northeast Brazil)
    Neves, I. de A.
    da Camara, C. A. G.
    de Oliviera, J. C. S.
    de Almeida, A. V.
    JOURNAL OF ESSENTIAL OIL RESEARCH, 2011, 23 (01) : 23 - 26
12345