Bursting in Two-Coupled Cells Network in the Pre-Botzinger Complex

被引:0
|
作者
Duan, Lixia [1 ]
Yuan, Dandan [1 ]
Chen, Xi [1 ]
机构
[1] North China Univ Technol, Coll Sci, Beijing, Peoples R China
来源
ADVANCES IN COGNITIVE NEURODYNAMICS (IV) | 2015年
关键词
Respiratory rhythm generation; Pre-Botzinger complex; Bursting patterns; Two-cell network; Bifurcation analysis; RESPIRATORY RHYTHM GENERATION; PACEMAKER NEURONS; MODELS;
D O I
10.1007/978-94-017-9548-7_49
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The persistent sodium play an important role in respiratory rhythm generation in neurons of the pre-Botzinger complex. We study the bursting patterns and transition mechanisms in a two-cell network model by both fast/slow decomposition and two-parameter bifurcation analysis. The results show the transitions of different types of bursting are not synchronized. This work provide a future understanding of that how NaP current works in respiratory rhythm generation.
引用
收藏
页码:347 / 351
页数:5
相关论文
共 50 条
  • [41] Bifurcations underlying sigh and eupnea rhythmic transition in a pre-Botzinger complex model
    Hua, Hongtao
    Gu, Huaguang
    EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS, 2022, 231 (22-23) : 4109 - 4116
  • [42] Dbx1 Pre-Botzinger Complex Interneurons Comprise the Core Inspiratory Oscillator for Breathing in Unanesthetized Adult Mice
    Vann, Nikolas C.
    Pham, Francis D.
    Dorst, Kaitlyn E.
    Del Negro, Christopher A.
    ENEURO, 2018, 5 (03)
  • [43] Clinically Relevant Infusion Rates of μ-Opioid Agonist Remifentanil Cause Bradypnea in Decerebrate Dogs but not Via Direct Effects in the pre-Botzinger Complex Region
    Mustapic, Sanda
    Radocaj, Tomislav
    Sanchez, Antonio
    Dogas, Zoran
    Stucke, Astrid G.
    Hopp, Francis A.
    Stuth, Eckehard A. E.
    Zuperku, Edward J.
    JOURNAL OF NEUROPHYSIOLOGY, 2010, 103 (01) : 409 - 418
  • [44] Most inspiratory neurons in the pre-Botzinger complex are suppressed during vomiting in dogs
    Fukuda, H
    Koga, T
    BRAIN RESEARCH, 1997, 763 (01) : 30 - 38
  • [45] Modulation of expiratory motor output evoked by chemical activation of pre-Botzinger complex in vivo
    Solomon, IC
    RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY, 2002, 130 (03) : 235 - 251
  • [46] Substitution of extracellular Ca2+ by Sr2+ prolongs inspiratory burst in pre-Botzinger complex inspiratory neurons
    Morgado-Valle, Consuelo
    Fernandez-Ruiz, Juan
    Lopez-Meraz, Leonor
    Beltran-Parrazal, Luis
    JOURNAL OF NEUROPHYSIOLOGY, 2015, 113 (04) : 1175 - 1183
  • [47] Hypercapnic and hypoxic responses require intact neural transmission from the pre-Botzinger complex
    Wu, MF
    Haxhiu, MA
    Johnson, SM
    RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY, 2005, 146 (01) : 33 - 46
  • [48] The effect of lamotrigine and other antiepileptic drugs on respiratory rhythm generation in the pre-Botzinger complex
    Layer, Nikolas
    Brandes, Janine
    Luehrs, Philipp Justus
    Wuttke, Thomas, V
    Koch, Henner
    EPILEPSIA, 2021, 62 (11) : 2790 - 2803
  • [49] Neuroanatomical characteristics of the human pre-Botzinger complex and its involvement in neurodegenerative brainstem diseases
    Schwarzacher, Stephan W.
    Rueb, Udo
    Deller, Thomas
    BRAIN, 2011, 134 : 24 - 35
  • [50] Focal acidosis in the pre-Botzinger complex area of awake goats induces a mild tachypnea
    Krause, K. L.
    Forster, H. V.
    Davis, S. E.
    Kiner, T.
    Bonis, J. M.
    Pan, L. G.
    Qian, B.
    JOURNAL OF APPLIED PHYSIOLOGY, 2009, 106 (01) : 241 - 250