Epidemiology of gout

被引：343
作者：
Roddy, Edward [1 ]
Doherty, Michael [2 ]
机构：
[1] Keele Univ, Arthrit Res UK Primary Care Ctr, Keele ST5 5BG, Staffs, England
[2] City Hosp, Nottingham NG5 1PB, England
来源：
ARTHRITIS RESEARCH & THERAPY | 2010年 / 12卷 / 06期
关键词：
QUALITY-OF-LIFE; URIC-ACID CONCENTRATIONS; CORONARY-HEART-DISEASE; INCIDENT GOUT; RISK-FACTORS; METABOLIC SYNDROME; HIGH PREVALENCE; PRIMARY-CARE; DIURETIC USE; FOLLOW-UP;
D O I：
10.1186/ar3199
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Gout is the most prevalent form of inflammatory arthropathy. Several studies suggest that its prevalence and incidence have risen in recent decades. Numerous risk factors for the development of gout have been established, including hyperuricaemia, genetic factors, dietary factors, alcohol consumption, metabolic syndrome, hypertension, obesity, diuretic use and chronic renal disease. Osteoarthritis predisposes to local crystal deposition. Gout appears to be an independent risk factor for all-cause mortality and cardiovascular mortality and morbidity, additional to the risk conferred by its association with traditional cardiovascular risk factors.
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页数：11
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