Elemental tellurium mediated synthesis of 2-(trifluoromethyl)oxazoles using trifluoroacetic anhydride as reagent

被引：57
作者：
Luo, Beibei [1 ]
Weng, Zhiqiang [1 ]
机构：
[1] Fuzhou Univ, Coll Chem, State Key Lab Photocatalysis Energy & Environm, Fuzhou 350108, Fujian, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2018年 / 54卷 / 76期
基金：
中国国家自然科学基金;
关键词：
OXIME ACETATES; 2,5-DISUBSTITUTED OXAZOLES; N-PROPARGYLAMIDES; CYCLIZATION; STRATEGY; TRIFLUOROMETHYLATION; ALKALOIDS; CHEMISTRY; DISCOVERY;
D O I：
10.1039/c8cc05670f
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An elemental tellurium mediated synthesis of 2-(trifluoromethyl)oxazoles from the reaction of acetophenone oxime acetates with trifluoroacetic anhydride has been developed. This new tandem cyclization proceeds in good to excellent yields via a SET reduction followed by a 5-endo-trig pathway. Some of the title compounds showed fungicidal and insecticidal activities.
引用
收藏
页码：10750 / 10753
页数：4
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