Expression cloning of gamma interferon-inducing antigens of Mycobacterium avium subsp paratuberculosis

被引：27

作者：

Nagata, R ^{[1
]}

Muneta, Y ^{[1
]}

Yoshihara, K ^{[1
]}

Yokomizo, Y ^{[1
]}

Mori, Y ^{[1
]}

机构：

[1] Natl Inst Anim Hlth, Immune Syst Sect, Dept Immunol, Tsukuba, Ibaraki 3050856, Japan

来源：

INFECTION AND IMMUNITY | 2005年 / 73卷 / 06期

关键词：

D O I：

10.1128/IAI.73.6.3778-3782.2005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Three recombinant proteins, Map10, Map39, and Map41, produced based on nucleotide sequences obtained from the screening of Mycobacterium avium subsp. paratuberculosis genomic library expressed in Escherichia coli significantly elicited gamma interferon production in peripheral blood mononuclear cells from infected cattle. Two of these proteins were members of the PPE protein family.

引用

页码：3778 / 3782

页数：5

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