Randomized study of the OF Bioavailability of different formulations of coenzyme Q10 (Ubiquinone)

被引：17
|
作者：
Constantinescu, Radu
McDermott, Michael R.
DiCenzo, Robert
de Blieck, Elisabeth A.
Hyson, H. Christopher
Beal, M. Flint
Bednarczyk, Edward M.
Bogdanov, Mikhail
Metakis, Linda J.
Browne, Susan E.
Lorenzo, Beverly J.
Ravina, Bernard
Kieburtz, Karl
机构：
[1] Univ Rochester, Med Ctr, Clin Trials Coordinat Ctr, Dept Neurol, Rochester, NY 14620 USA
[2] Univ Rochester, Med Ctr, Dept Biostat & Computat Biol, Rochester, NY 14642 USA
[3] SUNY Buffalo, Dept Pharm Practice, Buffalo, NY 14260 USA
[4] Hlth Sci Ctr, London, ON, Canada
[5] Cornell Univ, Weill Med Coll, New York, NY USA
来源：
JOURNAL OF CLINICAL PHARMACOLOGY | 2007年 / 47卷 / 12期
关键词：
coenzyme Q(10); bioavailability; oral formulations; bioequivalence;
D O I：
10.1177/0091270007307571
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
[No abstract available]
引用
收藏
页码：1580 / 1586
页数：7
相关论文
共 50 条
  • [21] Physicochemical and pharmacokinetic characterization of water-soluble Coenzyme Q10 formulations
    Hatanaka, Junya
    Kimura, Yoshihiro
    Lai-Fu, Zhogn
    Onoue, Satomi
    Yamada, Shizuo
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2008, 363 (1-2) : 112 - 117
  • [22] Enhancement of oral bioavailability of coenzyme Q10 by complexation with γ-cyclodextrin in healthy adults
    Terao, Keiji
    Nakata, Daisuke
    Fukumi, Hiroshi
    Schmid, Gerhard
    Arima, Hidetoshi
    Hirayama, Fumitoshi
    Uekama, Kaneto
    NUTRITION RESEARCH, 2006, 26 (10) : 503 - 508
  • [23] Relative bioavailability of two forms of a novel water-soluble coenzyme Q10
    Zmitek, Janko
    Smidovnik, Andrej
    Fir, Maja
    Prosek, Mirko
    Zmitek, Katja
    Walczak, Jaroslaw
    Pravst, Igor
    ANNALS OF NUTRITION AND METABOLISM, 2008, 52 (04) : 281 - 287
  • [24] Stability and bioequivalence studies of two marketed formulations of coenzyme Q10 in beagle dogs
    Kommuru, TR
    Ashraf, M
    Khan, MA
    Reddy, IK
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1999, 47 (07) : 1024 - 1028
  • [25] Enhancing solubility and bioavailability of coenzyme Q10: formulation of solid dispersions using Soluplus® as a carrier
    Lamichhane, Shrawani
    Seo, Jo-Eun
    Keum, Taekwang
    Noh, Gyubin
    Bashyal, Santosh
    Cho, Seong-Wan
    Lee, Eun-Hee
    Lee, Sangkil
    ARCHIVES OF PHARMACAL RESEARCH, 2022, 45 (01) : 29 - 37
  • [26] Enhanced oral bioavailability of Coenzyme Q10 by self-emulsifying drug delivery systems
    Balakrishnan, Prabagar
    Lee, Beom-Jin
    Oh, Dong Hoon
    Kim, Jong Oh
    Lee, Young-Im
    Kim, Dae-Duk
    Jee, Jun-Pil
    Lee, Yong-Bok
    Woo, Jong Soo
    Yong, Chul Soon
    Choi, Han-Gon
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2009, 374 (1-2) : 66 - 72
  • [27] Enhancing solubility and bioavailability of coenzyme Q10: formulation of solid dispersions using Soluplus® as a carrier
    Shrawani Lamichhane
    Jo-Eun Seo
    Taekwang Keum
    Gyubin Noh
    Santosh Bashyal
    Seong-Wan Cho
    Eun-Hee Lee
    Sangkil Lee
    Archives of Pharmacal Research, 2022, 45 : 29 - 37
  • [28] TPGS-chitosome as an effective oral delivery system for improving the bioavailability of Coenzyme Q10
    Shao, Yating
    Yang, Liang
    Han, Hyo-Kyung
    EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2015, 89 : 339 - 346
  • [29] Randomized, double-blinded, controlled trial of the effects of coenzyme Q10 supplementation on plasma coenzyme Q10 concentration in dogs with myxomatous mitral valve disease
    Druzhaeva, Natalia
    Petric, Aleksandra Domanjko
    Tavcar-Kalcher, Gabrijela
    Babic, Janja
    Svete, Alenka Nemec
    AMERICAN JOURNAL OF VETERINARY RESEARCH, 2021, 82 (04) : 280 - 285
  • [30] The coenzyme Q10 content of food supplements
    Pravst, Igor
    Zmitek, Katja
    JOURNAL FUR VERBRAUCHERSCHUTZ UND LEBENSMITTELSICHERHEIT-JOURNAL OF CONSUMER PROTECTION AND FOOD SAFETY, 2011, 6 (04): : 457 - 463
12345