MicroRNAs in Hypertrophic, Arrhythmogenic and Dilated Cardiomyopathy

被引：18

作者：

Chiti, Enrica ^{[1
]}

Paolo, Marco ^{[2
]}

Turillazzi, Emanuela ^{[2
]}

Rocchi, Anna ^{[2
]}

机构：

[1] Scuola Super Sant Anna, Inst Life Sci, I-56124 Pisa, Italy

[2] Univ Pisa, Inst Legal Med, Dept Surg Pathol, Mol & Crit Area, Via Roma 55, I-56126 Pisa, Italy

来源：

DIAGNOSTICS | 2021年 / 11卷 / 09期

关键词：

microRNAs; biomarkers; inherited cardiomyopathies; dilated cardiomyopathy; arrhythmogenic cardiomyopathy; hypertrophic cardiomyopathy; RIGHT-VENTRICULAR CARDIOMYOPATHY; MYOCARDIAL-INFARCTION; CARDIAC-HYPERTROPHY; TASK-FORCE; CIRCULATING MICRORNAS; EUROPEAN-SOCIETY; DOWN-REGULATION; DIAGNOSIS; EXPRESSION; HEART;

D O I：

10.3390/diagnostics11091720

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

MicroRNAs (miRNAs) are a class of non-coding RNAs of about 20 nucleotides in length, involved in the regulation of many biochemical pathways in the human body. The level of miRNAs in tissues and circulation can be deregulated because of altered pathophysiological mechanisms; thus, they can be employed as biomarkers for different pathological conditions, such as cardiac diseases. This review summarizes published findings of these molecular biomarkers in the three most common structural cardiomyopathies: human dilated, arrhythmogenic and hypertrophic cardiomyopathy.

引用

页数：18

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