Prevention of cisplatin-induced ototoxicity in children and adolescents with cancer: a clinical practice guideline

被引：97

作者：

Freyer, David R. ^{[1
,2
,3
]}

Brock, Penelope R. ^{[4
]}

Chang, Kay W. ^{[5
]}

Dupuis, L. Lee ^{[6
,7
,9
]}

Epelman, Sidnei ^{[10
]}

Knight, Kristin ^{[11
]}

Mills, Denise ^{[8
,12
]}

Phillips, Robert ^{[13
,14
]}

Potter, Emma ^{[15
]}

Risby, Demie ^{[16
]}

Simpkin, Philippa

Sullivan, Michael ^{[17
,18
]}

Cabral, Sandra ^{[12
]}

Robinson, Paula D. ^{[12
]}

Sung, Lillian ^{[7
,8
]}

机构：

[1] Childrens Hosp Los Angeles, Childrens Ctr Canc & Blood Dis, Los Angeles, CA 90027 USA

[2] Univ Southern Calif, Keck Sch Med, Dept Pediat, Los Angeles, CA 90007 USA

[3] Univ Southern Calif, Keck Sch Med, Dept Med, Los Angeles, CA 90007 USA

[4] Great Ormond St Hosp Sick Children, Dept Haematol & Oncol, London, England

[5] Stanford Univ, Dept Otolaryngol Head & Neck Surg, Palo Alto, CA 94304 USA

[6] Hosp Sick Children, Dept Pharm, Toronto, ON, Canada

[7] Hosp Sick Children, Res Inst, Child Hlth Evaluat Sci, Toronto, ON, Canada

[8] Hosp Sick Children, Div Haematol & Oncol, Toronto, ON M5G 1X8, Canada

[9] Univ Toronto, Leslie Dan Fac Pharm, Toronto, ON, Canada

[10] Casa Saude Santa Marcelina, Dept Pediat Oncol, Sao Paulo, Brazil

[11] Oregon Hlth & Sci Univ, Doernbecher Childrens Hosp, Pediat Audiol, Portland, OR 97201 USA

[12] Pediat Oncol Grp Ontario, Toronto, ON, Canada

[13] Leeds Teaching Hosp, NHS Trust, Dept Haematol & Oncol, Leeds, W Yorkshire, England

[14] Univ York, Ctr Reviews & Disseminat, York, N Yorkshire, England

[15] Royal Marsden Hosp, Div Oncol, London, England

[16] Great Ormond St Hosp Sick Children, London, England

[17] Royal Childrens Hosp, Childrens Canc Ctr, Melbourne, Vic, Australia

[18] Univ Melbourne, Fac Med, Dept Paediat, Melbourne, Vic, Australia

来源：

LANCET CHILD & ADOLESCENT HEALTH | 2020年 / 4卷 / 02期

基金：

英国医学研究理事会;

关键词：

INDUCED HEARING-LOSS; PLATINUM-INDUCED OTOTOXICITY; HIGH-DOSE CISPLATIN; INDUCED TOXICITIES; N-ACETYLCYSTEINE; DOUBLE-BLIND; NECK-CANCER; SODIUM THIOSULFATE; PHASE-II; PROTECTION;

D O I：

10.1016/S2352-4642(19)30336-0

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Despite ototoxicity being a prevalent consequence of cisplatin chemotherapy, little guidance exists on interventions to prevent this permanent and progressive adverse event. To develop a clinical practice guideline for the prevention of cisplatin-induced ototoxicity in children and adolescents with cancer, we convened an international, multidisciplinary panel of experts and patient advocates to update a systematic review of randomised trials for the prevention of cisplatin-induced ototoxicity. The systematic review identified 27 eligible adult and paediatric trials that evaluated amifostine, sodium diethyldithiocarbamate or disulfiram, systemic sodium thiosulfate, intratympanic therapies, and cisplatin infusion duration. Regarding systemic sodium thiosulfate, the panel made a strong recommendation for administration in non-metastatic hepatoblastoma, a weak recommendation for administration in other non-metastatic cancers, and a weak recommendation against its routine use in metastatic cancers. Amifostine, sodium diethyldithiocarbamate, and intratympanic therapy should not be routinely used. Cisplatin infusion duration should not be altered as a means to reduce ototoxicity. Further research to determine the safety of sodium thiosulfate in patients with metastatic cancer is encouraged.

引用

页码：141 / 150

页数：10

共 51 条

[1] In-vitro perforation of the round window membrane via direct 3-D printed microneedles [J].

Aksit, Aykut ;

Arteaga, Daniel N. ;

Arriaga, Miguel ;

Wang, Xun ;

Watanabe, Hirobumi ;

Kasza, Karen E. ;

Lalwani, Anil K. ;

Kysar, Jeffrey W. .

BIOMEDICAL MICRODEVICES, 2018, 20 (02)

[2]

Bird Philip A, 2018, Adv Otorhinolaryngol, V81, P114, DOI 10.1159/000485541

[3] Sodium Thiosulfate for Protection from Cisplatin-Induced Hearing Loss [J].

Brock, P. R. ;

Maibach, R. ;

Childs, M. ;

Rajput, K. ;

Roebuck, D. ;

Sullivan, M. J. ;

Laithier, V. ;

Ronghe, M. ;

Dall'Igna, P. ;

Hiyama, E. ;

Brichard, B. ;

Skeen, J. ;

Mateos, M. E. ;

Capra, M. ;

Rangaswami, A. A. ;

Ansari, M. ;

Rechnitzer, C. ;

Veal, G. J. ;

Covezzoli, A. ;

Brugieres, L. ;

Perilongo, G. ;

Czauderna, P. ;

Morland, B. ;

Neuwelt, E. A. .

NEW ENGLAND JOURNAL OF MEDICINE, 2018, 378 (25) :2376-2385

[4] Platinum-Induced Ototoxicity in Children: A Consensus Review on Mechanisms, Predisposition, and Protection, Including a New International Society of Pediatric Oncology Boston Ototoxicity Scale [J].

Brock, Penelope R. ;

Knight, Kristin R. ;

Freyer, David R. ;

Campbell, Kathleen C. M. ;

Steyger, Peter S. ;

Blakley, Brian W. ;

Rassekh, Shahrad R. ;

Chang, Kay W. ;

Fligor, Brian J. ;

Rajput, Kaukab ;

Sullivan, Michael ;

Neuwelt, Edward A. .

JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (19) :2408-2417

[5] Subgroup analyses in randomized trials: risks of subgroup-specific analyses; power and sample size for the interaction test [J].

Brookes, ST ;

Whitely, E ;

Egger, M ;

Smith, GD ;

Mulheran, PA ;

Peters, TJ .

JOURNAL OF CLINICAL EPIDEMIOLOGY, 2004, 57 (03) :229-236

[6] Grading quality of evidence and strength of recommendations in clinical practice guidelines [J].

Brozek, J. L. ;

Akl, E. A. ;

Alonso-Coello, P. ;

Lang, D. ;

Jaeschke, R. ;

Williams, J. W. ;

Phillips, B. ;

Lelgemann, M. ;

Lethaby, A. ;

Bousquet, J. ;

Guyatt, G. H. ;

Schuenemann, H. J. .

ALLERGY, 2009, 64 (05) :669-677

[7] Recommendations for ototoxicity surveillance for childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCare Consortium [J].

Clemens, Eva ;

van den Heuvel-Eibrink, Marry M. ;

Mulder, Renee L. ;

Kremer, Leontien C. M. ;

Hudson, Melissa M. ;

Skinner, Roderick ;

Constine, Louis S. ;

Bass, Johnnie K. ;

Kuehni, Claudia E. ;

Langer, Thorsten ;

van Dalen, Elvira C. ;

Bardi, Edith ;

Bonne, Nicolas-Xavier ;

Brock, Penelope R. ;

Brooks, Beth ;

Carleton, Bruce ;

Caron, Eric ;

Chang, Kay W. ;

Johnston, Karen ;

Knight, Kristin ;

Nathan, Paul C. ;

Orgel, Etan ;

Prasad, Pinki K. ;

Rottenberg, Jan ;

Scheinemann, Katrin ;

de Vries, Andrica C. H. ;

Walwyn, Thomas ;

Weiss, Annette ;

Zehnhoff-Dinnesen, Antoinette Am ;

Cohn, Richard J. ;

Landier, Wendy ;

Kadan-Lottick, Nina ;

Levitt, Gill ;

Hoetink, Alex ;

Mussman, John .

LANCET ONCOLOGY, 2019, 20 (01) :E29-E41

[8] Hearing loss after platinum treatment is irreversible in noncranial irradiated childhood cancer survivors [J].

Clemens, Eva ;

de Vries, Andrica C. H. ;

Zehnhoff-Dinnesen, Antoinette Am ;

Tissing, Wim J. E. ;

Loonen, Jacqueline J. ;

Pluijm, Saskia F. M. ;

van Dulmen-den Broeder, Eline ;

Bresters, Dorine ;

Versluys, Birgitta ;

Kremer, Leontien C. M. ;

van der Pal, Helena J. ;

Neggers, Sebastian J. C. C. M. ;

van Grotel, Martine ;

van den Heuvel-Eibrink, Marry M. .

PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2017, 34 (02) :120-129

[9] NB87 induction protocol for stage 4 neuroblastoma in children over 1 year of age: A report from the French Society of Pediatric Oncology [J].

Coze, C ;

Hartmann, O ;

Michon, J ;

Frappaz, D ;

Dusol, F ;

Rubie, H ;

Plouvier, E ;

Leverger, G ;

Bordigoni, P ;

Behar, C ;

Beck, D ;

Mechinaud, F ;

Bergeron, C ;

Plantaz, D ;

Otten, J ;

Zucker, JM ;

Philip, T ;

Bernard, JL .

JOURNAL OF CLINICAL ONCOLOGY, 1997, 15 (12) :3433-3440

[10] COAST (Cisplatin ototoxicity attenuated by aspirin trial): A phase II double-blind, randomised controlled trial to establish if aspirin reduces cisplatin induced hearing-deloss [J].

Crabb, Simon J. ;

Martin, Karen ;

Abab, Julia ;

Ratcliffe, Ian ;

Thornton, Roger ;

Lineton, Ben ;

Ellis, Mary ;

Moody, Ronald ;

Stanton, Louise ;

Galanopoulou, Angeliki ;

Maishman, Tom ;

Geldart, Thomas ;

Bayne, Mike ;

Davies, Joe ;

Lamb, Carolynn ;

Popat, Sanjay ;

Joffe, Johnathan K. ;

Nutting, Chris ;

Chester, John ;

Hartley, Andrew ;

Thomas, Gareth ;

Ottensmeier, Christian ;

Huddart, Robert ;

King, Emma .

EUROPEAN JOURNAL OF CANCER, 2017, 87 :75-83

← 1 2 3 4 5 6 →