Future challenges and treatment of Staphylococcus aureus bacteremia with emphasis on MRSA

被引：65

作者：

Rasmussen, Rasmus V. ^{[1
]}

Fowler, Vance G., Jr. ^{[2
]}

Skov, Robert ^{[3
]}

Bruun, Niels E. ^{[1
]}

机构：

[1] Univ Copenhagen Hosp, Dept Cardiol, DK-2100 Copenhagen, Denmark

[2] Duke Univ, Med Ctr, Div Infect Dis, Durham, NC USA

[3] Statens Serum Inst, Staphylococcal Lab, DK-2300 Copenhagen, Denmark

来源：

FUTURE MICROBIOLOGY | 2011年 / 6卷 / 01期

关键词：

bacteremia; epidemiology; Infective endocarditis; MRSA; Staphylococcus aureus; treatment; BLOOD-STREAM INFECTIONS; MINIMUM INHIBITORY CONCENTRATION; SKIN-STRUCTURE INFECTIONS; PANTON-VALENTINE LEUKOCIDIN; NATIVE VALVE ENDOCARDITIS; GRAM-POSITIVE INFECTIONS; DOUBLE-BLIND TRIAL; METHICILLIN-RESISTANT; COMPLICATED SKIN; VANCOMYCIN-INTERMEDIATE;

D O I：

10.2217/FMB.10.155

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Staphylococcus aureus bacteremia (SAB) is an urgent medical problem due to its growing frequency and its poor associated outcome. As healthcare delivery increasingly involves invasive procedures and implantable devices, the number of patients at risk for SAB and its complications is likely to grow. Compounding this problem is the growing prevalence of methicillin-resistant S. aureus (MRSA) and the dwindling efficacy of vancomycin, long the treatment of choice for this pathogen. Despite the recent availability of several new antibiotics for S. aureus, new strategies for treatment and prevention are required for this serious, common cause of human infection.

引用

页码：43 / 56

页数：14

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