MICROFLUIDIC IMPEDANCE CYTOMETRY: MEASURING SINGLE CELLS AT HIGH SPEED

被引:1
作者
Sun, Tao [1 ]
Morgan, Hywel [1 ]
机构
[1] Univ Southampton, Nano Res Grp, Sch Elect & Comp Sci, Southampton SO17 1BJ, Hants, England
来源
MICROFLUIDICS BASED MICROSYSTEMS: FUNDAMENTALS AND APPLICATIONS | 2010年
基金
英国工程与自然科学研究理事会;
关键词
MICRO-COULTER COUNTER; MATHEMATICAL TREATMENT; ELECTRIC IMPEDANCE; DIELECTRIC-SPECTROSCOPY; PARTICLE IMPEDANCE; BIOLOGICAL CELLS; FLOW-CYTOMETRY; CHIP; CONDUCTIVITY; SUSPENSIONS;
D O I
10.1007/978-90-481-9029-4_24
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
High throughput single cell microfluidic analysis platforms offer the ability to characterize large numbers of individual cells (or more generally particles) at high speed. Miniature flow cytometers offer new methods for the rapid analysis of single cells. Impedance analysis of single cells provides information on cell size (volume), membrane and cytoplasmic characteristics. The technology has developed rapidly and offers the prospects of new approaches for counting and differentiating cells with applications from basic research to point of care diagnostics.
引用
收藏
页码:507 / 527
页数:21
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