Foxo1 and Foxo3 help Foxp3

被引:30
|
作者
Ohkura, Naganari [1 ,2 ]
Sakaguchi, Shimon [1 ,2 ]
机构
[1] Osaka Univ, World Premier Int Immunol Frontier Res Ctr, Dept Expt Immunol, Suita, Osaka 5650871, Japan
[2] Kyoto Univ, Inst Frontier Med Sci, Dept Expt Pathol, Kyoto 6068507, Japan
关键词
REGULATORY T-CELLS; EXPRESSION; DIFFERENTIATION; RECEPTOR; MTOR; AKT;
D O I
10.1016/j.immuni.2010.12.004
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In this issue of Immunity, Kerdiles et al. (2010) report that Foxo transcription factors are essential for the development and function of Foxp3-expressing regulatory T (Treg) cells via controlling the expression of genes associated with Treg cell function.
引用
收藏
页码:835 / 837
页数:3
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