Fecal microbiota transplantation in a kidney transplant recipient with recurrent urinary tract infection

被引:50
作者
Biehl, Lena M. [1 ,2 ]
Aguilar, Rebeca Cruz [1 ,2 ]
Farowski, Fedja [1 ]
Hahn, Werner
Nowag, Angela [3 ,4 ]
Wisplinghoff, Hilmar [3 ,4 ,5 ]
Vehreschild, Maria J. G. T. [1 ,2 ]
机构
[1] Univ Hosp Cologne, Dept Internal Med 1, Cologne, Germany
[2] German Ctr Infect Res, Partner Site Bonn Cologne, Cologne, Germany
[3] Wisplinghoff Labs, Cologne, Germany
[4] Univ Cologne, Inst Med Microbiol Immunol & Hyg, Cologne, Germany
[5] Witten Herdecke Univ, Inst Virol & Med Microbiol, Witten, Germany
关键词
Recurrent urinary tract infection; Fecal microbiota transplantation; Urinary microbiome; Non-antibiotic prophylaxis; CLOSTRIDIUM-DIFFICILE INFECTION;
D O I
10.1007/s15010-018-1190-9
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Purpose We report on a kidney transplant recipient treated with fecal microbiota transplantation (FMT) for recurrent urinary tract infections. Methods FMT was administered via frozen capsulized microbiota. Before and after FMT, urinary, fecal and vaginal microbiota compositions were analyzed. Results The patient remained without symptoms after FMT. Conclusions Underlying mechanisms of action need to be addressed in depth by future research.
引用
收藏
页码:871 / 874
页数:4
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