Oncogenic potential of Human Papillomavirus (HPV) and its relation with cervical cancer

被引:120
作者
Faridi, Rabia [1 ]
Zahra, Amreen [1 ]
Khan, Khalida [2 ]
Idrees, Muhammad [1 ]
机构
[1] Univ Punjab, Natl Ctr Excellence Mol Biol, Div Mol Virol, Lahore 53700, Pakistan
[2] Univ Punjab, Ctr Integrated Mt Res, Lahore 54590, Pakistan
关键词
PARTICLE VACCINE; RISK-FACTORS; HAPTOGLOBIN GENOTYPE; SUSTAINED EFFICACY; SEXUAL-BEHAVIOR; GENE-PRODUCT; YOUNG-WOMEN; INFECTION; TYPE-16; PREVALENCE;
D O I
10.1186/1743-422X-8-269
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Human Papillomavirus (HPV) is the most common cause of cervical cancer. Cervical cancer being the second most common cancer after lung cancer, affecting women of different age groups; has a prevalence of about 20% in young sexually active women. Among different types of HPV, HPV16 the major strain causing this cancer and is sexually transmitted had been unnoticed for decades. Keeping in mind the multiple risk factors related with cervical cancer such as early age sexual activities, teenage pregnancies, smoking, use of oral contraceptives, having multiple sex partners, hormone replacement therapies and various other unknown factors lead to the onset of the disease. Awareness for various diagnostic procedures such as Pap smears screening prove to be an effective way in eradicating the oncogenic potential of HPV.
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页数:8
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