Frequency of celiac disease in individuals with Down syndrome in the United States

被引：33
作者：
Mackey, J
Treem, WR
Worley, G
Boney, A
Hart, P
Kishnani, PS
机构：
[1] Duke Univ, Med Ctr, Dept Pediat, Div Med Genet, Durham, NC 27710 USA
[2] Duke Univ, Med Ctr, Dept Pediat, Div Gastroenterol & Nutr, Durham, NC 27710 USA
[3] Duke Univ, Med Ctr, Dept Pediat, Div Dev Pediat, Durham, NC 27710 USA
来源：
CLINICAL PEDIATRICS | 2001年 / 40卷 / 05期
关键词：
D O I：
10.1177/000992280104000502
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Ninety-three individuals with Down syndrome (DS) were screened to investigate the prevalence of celiac disease (CD) in the United States. Five of the 93 individuals were antiendomysial antibody (EMA) positive. Of the 5 who tested positive for EMA, 4 were biopsied, 1 refused biopsy. Three of the 4 individuals biopsied manifested changes of CD on small bowel biopsy. This gives a frequency of 3.2% of confirmed CD in our DS individuals and suggests the need for periodic screening for celiac disease in this population.
引用
收藏
页码：249 / 252
页数：4
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