Real-world Experience of Sotrovimab in High-risk, Immunocompromised COVID-19 Patients

被引：7
|
作者：
Birk, Navina K. [1 ]
Jain, Saniya [1 ]
Massoud, Louis [1 ]
Ramesh, Diya [1 ]
Monday, Lea [1 ]
Muma, Bruce [1 ]
Williams, Jonathan [1 ]
Alangaden, George [1 ]
Ramesh, Mayur [1 ]
机构：
[1] Henry Ford Hosp, Dept Internal Med, Div Infect Dis, Detroit, MI 48202 USA
来源：
OPEN FORUM INFECTIOUS DISEASES | 2022年 / 9卷 / 07期
关键词：
COVID-19; monoclonal antibody; sotrovimab; immunocompromised hosts; outcomes;
D O I：
10.1093/ofid/ofac282
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We completed a real-world analysis of 498 consecutive high-risk nonimmunocompromised and immunocompromised patients who received sotrovimab during the B.1.1.529 surge. Emergency department visits/hospitalizations and 30-day all-cause mortality between the 2 groups were similar. When administered early, sotrovimab is effective at preventing coronavirus disease 2019 progression in immunocompromised and nonimmunocompromised patients.
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页数：3
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