L-proline catalyzed solvent-free Knoevenagel condensation for the synthesis of 3-substituted coumarins

被引:60
|
作者
Karade, Nandkishor N. [1 ]
Gampawar, Sumit V.
Shinde, Sandeep V.
Jadhav, Wamanrao N.
机构
[1] Swami Ramanand Teerth Marathwada Univ, Sch Chem Sci, Nanded 431606, Maharashtra, India
[2] Dnyanopasak Coll, Parbhani 431401, Maharashtra, India
关键词
Knoevenagel condensation; coumarin; salicylaldehyde; L-proline; beta-ketoester; solvent-free synthesis;
D O I
10.1002/cjoc.200790311
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
L-Proline was utilized as an efficient organo-catalyst for the environmentally benign synthesis of 3-substituted. coumarins by the Knoevenagel condensation of substituted 2-hydroxybenzaldehydes with reactive methylene compounds under solvent free conditions.
引用
收藏
页码:1686 / 1689
页数:4
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