The Role of Human Papilloma Virus in Urological Malignancies

被引：1

作者：

Heidegger, Isabel ^{[1
]}

Borena, Wegene ^{[2
]}

Pichler, Renate ^{[1
]}

机构：

[1] Med Univ Innsbruck, Dept Urol, A-6020 Innsbruck, Austria

[2] Med Univ Innsbruck, Dept Hyg Microbiol & Social Med, Div Virol, A-6020 Innsbruck, Austria

来源：

ANTICANCER RESEARCH | 2015年 / 35卷 / 05期

关键词：

HPV; prostate cancer; renal cell carcinoma; bladder cancer; testicular cancer; penile cancer; review; IN-SITU HYBRIDIZATION; LOWER GENITAL-TRACT; PROSTATE-CANCER; UROTHELIAL CARCINOMA; INFECTION; DNA; RISK; P53; HPV; PATHOGENESIS;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Human papillomavirus (HPV) is associated with cancer of the cervix uteri, penis, vulva, vagina, anus and oropharynx. However, the role of HPV infection in urological tumors is not yet clarified. HPV appears not to play a major causative role in renal and testicular carcinogenesis. However, HPV infection should be kept in mind regarding cases of prostate cancer, as well as in a sub-group of patients with bladder cancer with squamous differentiation. Concerning the role of HPV in penile cancer incidence, it is a recognized risk factor proven in a large number of studies. This short review provides an update regarding recent literature on HPV in urological malignancies, thereby, also discussing possible limitations on HPV detection in urological cancer.

引用

页码：2513 / 2519

页数：7

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