Prevalence and characterization of the mechanisms of macrolide, lincosamide, and streptogramin resistance in isolates of Streptococcus pneumoniae

被引：151
作者：
Johnston, NJ
De Azavedo, JC
Kellner, JD
Low, DE
机构：
[1] Mt Sinai Hosp, Dept Microbiol, Toronto, ON M5G 1X5, Canada
[2] Princess Margaret Hosp, Toronto, ON M4X 1K9, Canada
[3] Univ Toronto, Toronto, ON, Canada
[4] Alberta Childrens Hosp, Calgary, AB, Canada
[5] Univ Calgary, Calgary, AB, Canada
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1998年 / 42卷 / 09期
关键词：
D O I：
10.1128/AAC.42.9.2425
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Of a total of 147 erythromycin-resistant Streptococcus pneumoniae isolates, 64 (43.5%) were resistant to erythromycin, clindamycin, and streptogramin B (MLSB phenotype), 57 of which possessed the ermB gene. Eighty-two (55.8%) were resistant to erythromycin alone (M phenotype), 81 of which possessed the mefE gene. One was erythromycin and streptogramin B resistant but susceptible to clindamycin (MS phenotype) and possessed neither the erm gene nor the mefE gene.
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页码：2425 / 2426
页数：2
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