New Bioinspired Membrane Made of a Biological Ion Channel Confined into the Cylindrical Nanopore of a Solid-State Polymer.

被引：46

作者：

Balme, Sebastien ^{[1
]}

Janot, Jean-Marc ^{[2
]}

Berardo, Lydie ^{[1
]}

Henn, Francois ^{[1
]}

Bonhenry, Daniel ^{[3
]}

Kraszewski, Sebastian ^{[3
]}

Picaud, Fabien ^{[3
]}

Ramseyer, Christophe ^{[3
]}

机构：

[1] CNRS UM2 ENSCM UM1, Inst Charles Gerhardt, UMR 5253, F-34095 Montpellier 5, France

[2] CNRS UM2 ENSCM, Inst Europeen Membranes, UMR5635, F-34095 Montpellier 5, France

[3] Univ Franche Comte, CNRS, Inst UTINAM, UMR6213, F-25030 Besancon, France

来源：

NANO LETTERS | 2011年 / 11卷 / 02期

关键词：

Hybrid membrane; track-etched membrane; Gramicidin-A; ion diffusion; fluorescence spectroscopy; molecular dynamics simulation; CONFOCAL FLUORESCENCE; TRANSPORT PHENOMENA; GRAMICIDIN; PROTEINS; NANOFLUIDICS; ADSORPTION; POTASSIUM; MICA;

D O I：

10.1021/nl103841m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A hybrid nanoporous membrane made of a solid-state polymeric thin film in which an ion channel is confined is realized. The primary and extremely encouraging results obtained by confocal fluorescence spectroscopy and ion diffusion measurement demonstrate respectively that (i) the considered ion channel, that is, Gramicidin-A, can be confined selectively inside the nanopores and (ii) the ionic permeability of the membrane is enhanced. Atomistic molecular simulations are also reported and fruitfully compared to the experimental findings.

引用

页码：712 / 716

页数：5

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