A comparison of three disease-specific and two generic health-status measures to evaluate the outcome of pulmonary rehabilitation in COPD

被引:59
作者
Singh, SJ
Sodergren, SC
Hyland, ME
Williams, J
Morgan, MDL
机构
[1] Univ Hosp Leicester, NHS Trust, Dept Resp Med, Glenfield Hosp, Leicester LE3 9QP, Leics, England
[2] Univ Plymouth, Dept Psychol, Plymouth PL4 8AA, Devon, England
关键词
health status; pulmonary rehabilation; COPD;
D O I
10.1053/rmed.2000.0976
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The use of health status as an outcome measure is becoming more widespread in pulmonary rehabilitation. There are a number of health status measures but the choice remains uncertain. Three disease specific measures and two generic measures of health status were employed to observe their relative sensitivity to a 7-week course of pulmonary rehabilitation. Patients with stable chronic obstructive pulmonary disease (COPD) were recruited into a rehabilitation programme. They completed a shuttle-walking test and three disease-specific questionnaires: the Chronic Respiratory Questionnaire (CRQ), the St. George's Hospital Respiratory Questionnaire (SGRQ) and the Breathing Problems Questionnaire (BPQ). Patients also completed two generic questionnaires: a global quality-of-life scale and an activity checklist. Ninety-seven patients [58 male mean (sD) age 67 (87) years] completed the course over a 12-month period. The mean pre-rehabilitation (sD) FEV1 was 1.06 (0.59) 1. The shuttle-walking test and the treadmill-endurance test increased significantly after rehabilitation (P < 0.001). All three disease-specific questionnaires improved significantly (the CRQ and SGRQ improved beyond minimum clinically important difference). The global score improved significantly whilst the 'things people do' decreased. All three disease-specific measures were responsive to pulmonary rehabilitation. However the operator-led CRQ appears to be the most sensitive short-term outcome measure.
引用
收藏
页码:71 / 77
页数:7
相关论文
共 19 条
[1]  
*AM THOR SOC, 1996, AM J RESP CRIT CARE, V159, P1666
[2]   THE SICKNESS IMPACT PROFILE - DEVELOPMENT AND FINAL REVISION OF A HEALTH-STATUS MEASURE [J].
BERGNER, M ;
BOBBITT, RA ;
CARTER, WB ;
GILSON, BS .
MEDICAL CARE, 1981, 19 (08) :787-805
[3]   PSYCHOPHYSICAL BASES OF PERCEIVED EXERTION [J].
BORG, GAV .
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 1982, 14 (05) :377-381
[4]  
Cohen J., 1998, Statistical Power Analysis for the Behavioral Sciences, V2nd
[5]   Results at 1 year of outpatient multidisciplinary pulmonary rehabilitation: a randomised controlled trial [J].
Griffiths, TL ;
Burr, ML ;
Campbell, IA ;
Lewis-Jenkins, V ;
Mullins, J ;
Shiels, K ;
Turner-Lawlor, PJ ;
Payne, N ;
Newcombe, RG ;
Lonescu, AA ;
Thomas, J ;
Tunbridge, J .
LANCET, 2000, 355 (9201) :362-368
[6]   A MEASURE OF QUALITY-OF-LIFE FOR CLINICAL-TRIALS IN CHRONIC LUNG-DISEASE [J].
GUYATT, GH ;
BERMAN, LB ;
TOWNSEND, M ;
PUGSLEY, SO ;
CHAMBERS, LW .
THORAX, 1987, 42 (10) :773-778
[7]  
HARIJO T, 1998, AM J RESP CRIT CARE, V157, P785
[8]  
Hunt S, 1986, MEASURING HLTH STATU
[9]   DOMAINS, CONSTRUCTS AND THE DEVELOPMENT OF THE BREATHING PROBLEMS QUESTIONNAIRE [J].
HYLAND, ME ;
BOTT, J ;
SINGH, S ;
KENYON, CAP .
QUALITY OF LIFE RESEARCH, 1994, 3 (04) :245-256
[10]  
Hyland ME, 1998, QUAL LIFE RES, V7, P227, DOI 10.1023/A:1008826014337