Mass-spectroscopy phosphorylation profiling identified differential activation of signaling molecules via spleen tyrosine kinase in B-cell receptor signaling and stromal cell stimulation in DLBCL and CLL cells that are inhibited by GS-9973

被引：1

作者：

Di Paolo, Julie A. ^{[1
]}

Clarke, Astrid ^{[1
]}

Rong, Hong ^{[1
]}

Rousseau, Emma ^{[1
]}

机构：

[1] Gilead Sci Inc, Branford, CT USA

来源：

CANCER RESEARCH | 2014年 / 74卷 / 19期

关键词：

D O I：

10.1158/1538-7445.AM2014-4205

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

4205

引用

页数：1

共 5 条

[1] Clinical Activity of Entospletinib (GS-9973), a Selective Syk Inhibitor, in Patients with CLL Previously Treated with an Inhibitor of B-Cell Receptor Pathway Signaling
Sharman, Jeff P.
Shustov, Andrei R.
Smith, Mitchell R.
Boyd, Thomas E.
Hagenstad, Christopher
Kolibaba, Kathryn S.
Abella, Steve
He, Jing
Eng, Clarence
Hu, Jing
Reddy, Anita
Mitra, Siddhartha
Yasenchak, Christopher A.
Awan, Farrukh T.
BLOOD, 2015, 126 (23)
[2] Updated Results on the Clinical Activity of Entospletinib (GS-9973), a Selective Syk Inhibitor, in Patients with CLL Previously Treated with an Inhibitor of the B-Cell Receptor Signaling Pathway
Sharman, Jeffrey P.
Shustov, Andrei R.
Smith, Mitchell R.
Hagenstad, Christopher T.
Kolibaba, Kathryn S.
Abella-Dominicis, Esteban
Zhang, Danjie
Mitra, Siddhartha
Yasenchak, Christopher A.
Awan, Farrukh T.
BLOOD, 2016, 128 (22)
[3] Antigen receptor signaling induces differential tyrosine kinase activation and population stability in B-cell lymphoma
Hsueh, RC
Hammill, AK
Marches, R
Uhr, JW
Scheuermann, RH
MECHANISMS OF B CELL NEOPLASIA 1998, 1999, 246 : 299 - 305
[4] Amplification of Toll-like receptor-mediated signaling through spleen tyrosine kinase in human B-cell activation
Iwata, Shigeru
Yamaoka, Kunihiro
Niiro, Hiroaki
Nakano, Kazuhisa
Wang, Sheau-Pey
Akashi, Koichi
Tanaka, Yoshiya
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2012, 129 (06) : 1594 - +
[5] TRANSMEMBRANE SIGNALING VIA MHC CLASS-II MOLECULES IN B-CELLS - THE ROLE OF PROTEIN TYROSINE KINASE ACTIVATION IN THE INDUCTION OF B-CELL AGGREGATION
FULEIHAN, R
SPERTINI, F
GEHA, RS
CHATILA, TA
CLINICAL RESEARCH, 1991, 39 (02): : A304 - A304

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