Fragmentations and reactions of the organophosphate insecticide Diazinon and its oxygen analog diazoxon studied by electrospray ionization ion trap mass spectrometry

被引：18
作者：
Barr, JD
Bell, AJ
Bird, M
Mundy, JL
Murrell, J
Timperley, CM
Watts, P [1 ]
Ferrante, F
机构：
[1] Porton Down, Detect Dept, Salisbury SP4 0JG, Wilts, England
[2] Univ Southampton, Dept Chem, Southampton SO9 5NH, Hants, England
[3] Univ Palermo, Dipartmento Chim Fis F Accascina, I-90133 Palermo, Italy
来源：
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY | 2005年 / 16卷 / 04期
关键词：
D O I：
10.1016/j.jasms.2004.12.013
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The fragmentations and reactions of Diazinon and related compounds have been studied by electrospray ionization ion trap mass spectrometry. Several novel fragmentation and rearrangements have been observed, including an intramolecular thiono-thiolo rearrangement. The stability, in the gas-phase, of the protomers of 2-isopropyl-4-methyl-6-pyrimidinol has been demonstrated. The complexity of the gas phase ion processes observed suggest that, at present, caution Should be exercised in using this approach for the analysis of environmental and other samples until our understanding of these processes increases considerably. (J Am Soc Mass Spectrom 2005, 16, 515-523) (c) 2005 American Society for Mass Spectrometry
引用
收藏
页码：515 / 523
页数：9
相关论文
共 15 条
[1]   Analysis of organophosphorus pesticide residues by low energy tandem mass spectrometry using electrospray ionization [J].
Banoub, J ;
Gentil, E ;
Kiceniuk, J .
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY, 1995, 61 (02) :143-167
[2]   Fragmentations and reactions of three isotopically labelled dimethyl methylphosphonate ions produced by electrospray ionisation in an ion trap mass spectrometer [J].
Barr, JD ;
Bell, AJ ;
Konn, DO ;
Murrell, J ;
Timperley, CM ;
Waters, MJ ;
Watts, P .
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2002, 4 (11) :2200-2205
[3]  
BARR JD, UNPUB FRAGMENTATIONS
[4]   EQUILIBRATION STUDIES - PROTOMERIC EQUILIBRIA OF 2-HYDROXYPYRIDINES AND 4-HYDROXYPYRIDINES, 2-HYDROXYPYRIMIDINES AND 4-HYDROXYPYRIMIDINES,2-MERCAPTOPYRIDINES AND 4-MERCAPTOPYRIDINES, AND STRUCTURALLY RELATED COMPOUNDS IN GAS-PHASE [J].
BEAK, P ;
FRY, FS ;
LEE, J ;
STEELE, F .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (01) :171-179
[5]   DENSITY-FUNCTIONAL EXCHANGE-ENERGY APPROXIMATION WITH CORRECT ASYMPTOTIC-BEHAVIOR [J].
BECKE, AD .
PHYSICAL REVIEW A, 1988, 38 (06) :3098-3100
[6]   An ab initio and DFT study of the fragmentation and isomerisation of MeP(O)(OMe)+ [J].
Bell, AJ ;
Citra, A ;
Dyke, JM ;
Ferrante, F ;
Gagliardi, L ;
Watts, P .
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2004, 6 (06) :1213-1218
[7]   Fragmentation and reactions of organophosphate ions produced by electrospray ionization [J].
Bell, AJ ;
Despeyroux, D ;
Murrell, J ;
Watts, P .
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 1997, 165 :533-550
[8]   Fragmentation and reactions of two isomeric O-alkyl S-(2-dialkylamino)ethyl methylphosphonothiolates studied by electrospray ionization/ion trap mass spectrometry [J].
Bell, AJ ;
Murrell, J ;
Timperley, CM ;
Watts, P .
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2001, 12 (08) :902-910
[9]  
Frisch M.J., 2004, Gaussian 03
[10]  
Revision C.02
12