Artificial Light at Night Influences Clock-Gene Expression, Activity, and Fecundity in the Mosquito Culex pipiens f. molestus

被引:24
作者
Honnen, Ann-Christin [1 ,2 ,3 ]
Kypke, Janina L. [1 ,4 ]
Hoelker, Franz [1 ,5 ]
Monaghan, Michael T. [1 ,5 ,6 ]
机构
[1] Leibniz Inst Freshwater Ecol & Inland Fisheries I, Muggelseedamm 301-310, D-12587 Berlin, Germany
[2] Swiss Trop & Publ Hlth Inst, Socinstr 57, CH-4002 Basel, Switzerland
[3] Univ Basel, Peterspl 1, CH-4001 Basel, Switzerland
[4] Nat Hist Museum Denmark, Zool Museum, Univ Pk 15, DK-2100 Copenhagen, Denmark
[5] Free Univ Berlin, Inst Biol, Konigin Luise Str 1-3, D-14195 Berlin, Germany
[6] Berlin Ctr Genom Biodivers Res, Konigin Luise Str 6-8, D-14195 Berlin, Germany
关键词
Circadian clock; ALAN; Behavior; LED; Egg production; period; Clock; cycle; cryptochrome2; timeless; CIRCADIAN CLOCK; FLIGHT ACTIVITY; AEDES-AEGYPTI; DIPTERA; CULICIDAE; TIMELESS; VECTORS; CRYPTOCHROMES; TERRESTRIAL; MECHANISM;
D O I
10.3390/su11226220
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Light is an important environmental cue, and exposure to artificial light at night (ALAN) may disrupt organismal physiology and behavior. We investigated whether ALAN led to changes in clock-gene expression, diel activity patterns, and fecundity in laboratory populations of the mosquito Culex pipiens f. molestus (Diptera, Culicidae), a species that occurs in urban areas and is thus regularly exposed to ALAN. Populations were kept under 16 h:8h light:dark cycles or were subjected to an additional 3.5 h of light (100-300 lx) in the evenings. ALAN induced significant changes in expression in all genes studied, either alone (period) or as an interaction with time (timeless, cryptochrome2, Clock, cycle). Changes were sex-specific: period was down-regulated in both sexes, cycle was up-regulated in females, and Clock was down-regulated in males. ALAN-exposed mosquitoes were less active during the extra-light phase, but exposed females were more active later in the night. ALAN-exposed females also produced smaller and fewer eggs. Our findings indicate a sex-specific impact of ALAN on the physiology and behavior of Culex pipiens f. molestus and that changes in clock-gene expression, activity, and fecundity may be linked.
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页数:21
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