A concise synthesis of monoterpene pyridine alkaloid aucubinine B

被引：0
作者：
Yang, XX
Zhao, JR
Jia, XS
Yang, LW
Zhai, HB
机构：
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Lab Modern Synthet Organ Chem, Shanghai 200032, Peoples R China
[2] Shanghai Univ, Dept Chem, Shanghai 200436, Peoples R China
[3] Shanghai Univ, Coll Life Sci, Shanghai 100436, Peoples R China
来源：
CHINESE JOURNAL OF CHEMISTRY | 2003年 / 21卷 / 07期
关键词：
aucubinine B; monoterpene alkaloid; intramolecular Heck reaction;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Aucubinine B (4), a monoterpene alkaloid obtained from the metabolites of aucubin in the presence of human intestinal bacteria, has been synthesized from 3-bromo-4-pyridinecarboxaldehyde (5) in four steps with 39% overall yield. The construction of the cyclopenta [c] pyridine intermediate (7) was realized by an intramolecular Heck reaction.
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页码：970 / 971
页数：2
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