A novel one-pot, three-component synthesis of alkyl 6-aryl-3-methylpyridazine-4-carboxylates in water

被引：24

作者：

Rimaz, Mehdi ^{[1
]}

Khalafy, Jabbar ^{[1
]}

机构：

[1] Urmia Univ, Dept Chem, Orumiyeh 57154, Iran

来源：

ARKIVOC | 2010年

关键词：

Pyridazine; arylglyoxal; hydrazine; beta-ketoester; DIELS-ALDER REACTION; DERIVATIVES; PYRIDAZINE;

D O I：

10.3998/ark.5550190.0011.208

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of new alkyl 6-aryl-3-methylpyridazine-4-carboxylates were efficiently synthesized by a three-component reaction of beta-ketoesters with arylglyoxals in the presence of hydrazine hydrate in water at room temperature.

引用

页码：110 / 117

页数：8

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