An electromechanical model of cardiac tissue: Constitutive issues and electrophysiological effects

被引：100

作者：

Cherubini, C. ^{[1
]}

Filippi, S. ^{[1
]}

Nardinocchi, P. ^{[2
]}

Teresi, L. ^{[3
]}

机构：

[1] Univ Campus Biomedico, Lab Nonlinear Phys & Math Modeling, Rome, Italy

[2] Univ Roma La Sapienza, Dept Struct Engn & Geotech, Rome, Italy

[3] Univ Roma Tre, SMFM Math Struct Mat Phys, Rome, Italy

来源：

PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY | 2008年 / 97卷 / 2-3期

关键词：

electromechanics; mechano-electric feedback; mathematical physiology;

D O I：

10.1016/j.pbiomolbio.2008.02.001

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We present an electromechanical model of myocardium tissue coupling a modified FitzHugh-Nagumo type system, describing the electrical activity of the excitable media, with finite elasticity, endowed with the capability of describing muscle contractions. The high degree of deformability of the medium makes it mandatory to set the diffusion process in a moving domain, thereby producing a direct influence of the deformation on the electrical activity. Various mechanoelectric effects concerning the propagation of cylindrical waves, the rotating spiral waves, and the spiral breakups are discussed. (c) 2008 Elsevier Ltd. All rights reserved.

引用

页码：562 / 573

页数：12

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