VMAT and Step-and-Shoot IMRT in Head and Neck Cancer A Comparative Plan Analysis

被引:24
作者
Wiehle, Rolf [1 ]
Knippen, Stefan [1 ]
Grosu, Anca-Ligia [1 ]
Bruggmoser, Gregor [1 ]
Hodapp, Norbert [1 ]
机构
[1] Uniklin Freiburg, Klin Strahlenheilkunde, D-79106 Freiburg, Germany
关键词
IMRT; IMAT; VMAT; RapidArc; Head and neck cancer; Conformity index; Normal tissue sparing; MODULATED ARC THERAPY; PHOTON DOSE CALCULATION; RADIATION-THERAPY; RADIOTHERAPY; CONFORMITY; TOMOTHERAPY; ALGORITHM; SYSTEMS; MODELS; IMPACT;
D O I
10.1007/s00066-011-2267-x
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose: Rotational IMRT is a new technique, whose value still has to be assessed. We evaluated its adequacy for the treatment of head and neck (H&N) cancer compared to the well-established step-and-shoot IMRT. Materials and Methods: A total of 15 patients, who were treated with either IMRT (13 patients) or VMAT (2 patients) in the H&N region, were chosen. For each patient, a treatment plan with the respective other technique was calculated. To compare the resulting dose distributions, the dose-volume histograms (DVHs) were evaluated. To quantify the differences, a new quality index (QI) was introduced, as a measure of the planning target volume (PTV) coverage and homogeneity. A conformity function (CF) was defined to estimate normal tissue sparing. Results: The QI for VMAT amounts to 36.3, whereas for IMRT the mean value is 66.5, indicating better PTV coverage as well as less overdosage for the rotational technique. While the sparing of organs at risk (OAR) was similar for both techniques, the CF shows a significantly better sparing of healthy tissue for all doses with VMAT treatment. Conclusions: VMAT results in dose distributions for H&N patients that are at least comparable with treatments performed with step-and-shoot IMRT. Two new tools to quantify the quality of dose distributions are presented and have proven to be useful.
引用
收藏
页码:820 / 825
页数:6
相关论文
共 32 条
  • [1] A PENCIL BEAM MODEL FOR PHOTON DOSE CALCULATION
    AHNESJO, A
    SAXNER, M
    TREPP, A
    [J]. MEDICAL PHYSICS, 1992, 19 (02) : 263 - 273
  • [2] Single Arc Volumetric Modulated Arc Therapy of head and neck cancer
    Bertelsen, Anders
    Hansen, Christian R.
    Johansen, Jorgen
    Brink, Carsten
    [J]. RADIOTHERAPY AND ONCOLOGY, 2010, 95 (02) : 142 - 148
  • [3] Bruggmoser G, 2010, STRAHLENTHER ONKOL, V186, P101
  • [4] FEASIBILITY OF SINGLE-ISOCENTER VOLUMETRIC MODULATED ARC RADIOSURGERY FOR TREATMENT OF MULTIPLE BRAIN METASTASES
    Clark, Grant M.
    Popple, Richard A.
    Young, P. Edward
    Fiveash, John B.
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2010, 76 (01): : 296 - 302
  • [5] Delana A, 2009, STRAHLENTHER ONKOL, V185, P453, DOI 10.1007/s00066-009-1888-9
  • [6] Salivary gland sparing and improved target irradiation by conformal and intensity modulated irradiation of head and neck cancer
    Eisbruch, A
    Ship, JA
    Dawson, LA
    Kim, HM
    Bradford, CR
    Terrell, JE
    Chepeha, DB
    Teknos, TN
    Hogikyan, ND
    Anzai, Y
    Marsh, LH
    Ten Haken, RK
    Wolf, GT
    [J]. WORLD JOURNAL OF SURGERY, 2003, 27 (07) : 832 - 837
  • [7] Conformity index:: A review
    Feuvret, L
    Noël, G
    Mazeron, JJ
    Bey, P
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2006, 64 (02): : 333 - 342
  • [8] Intensity modulated therapy and inhomogeneous dose to the tumor: A note of caution
    Goitein, M
    Niemierko, A
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1996, 36 (02): : 519 - 522
  • [9] Hodapp N, 2008, STRAHLENTHER ONKOL, V184, P125
  • [10] Hodapp N, 2009, STRAHLENTHER ONKOL, V185, P126