Epidemiology and Clinical Features of Heart Failure with Preserved Ejection Fraction

被引：38

作者：

Teramoto, Kanako ^{[1
]}

Teng, Tiew-Hwa Katherine ^{[1
,2
,3
]}

Chandramouli, Chanchal ^{[1
,3
]}

Tromp, Jasper ^{[1
,3
,4
,5
]}

Sakata, Yasuhiko ^{[6
]}

Lam, Carolyn S. P. ^{[1
,3
,7
,8
]}

机构：

[1] Natl Heart Ctr, Singapore, Singapore

[2] Univ Western Australia, Sch Allied Hlth, Perth, Australia

[3] Duke Natl Univ Singapore, Med Sch, Singapore, Singapore

[4] Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore

[5] Natl Univ Hlth Syst, Singapore, Singapore

[6] Natl Cerebral & Cardiovasc Ctr, Osaka, Japan

[7] Univ Med Ctr Groningen, Dept Cardiol, Groningen, Netherlands

[8] Natl Heart Ctr Singapore, 5 Hosp Dr, Singapore 169609, Singapore

来源：

CARDIAC FAILURE REVIEW | 2022年 / 8卷

基金：

英国医学研究理事会;

关键词：

Heart failure with preserved ejection fraction; epidemiology; risk factors; comorbidities; cluster analysis; sex differences; prognosis; VENTRICULAR SYSTOLIC FUNCTION; QUALITY-OF-LIFE; ATRIAL-FIBRILLATION; SEX-DIFFERENCES; OUTCOMES; PREVALENCE; COMMUNITY; MORTALITY; CLASSIFICATION; DYSFUNCTION;

D O I：

10.15420/cfr.2022.06

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Heart failure (HF) with preserved ejection (HFpEF) constitutes a large and growing proportion of patients with HF around the world, and is now responsible for more than half of all HF cases in ageing societies. While classically described as a condition of elderly, hypertensive women, recent studies suggest heterogeneity in clinical phenotypes involving differential characteristics and pathophysiological mechanisms. Despite a paucity of disease-modifying therapy for HFpEF, an understanding of phenotypic similarities and differences among patients with HFpEF around the world provides the foundation to recognise the clinical condition for early treatment, as well as to identify modifiable risk factors for preventive intervention. This review summarises the epidemiology of HFpEF, its common clinical features and risk factors, as well as differences by age, comorbidities, race/ethnicity and geography.

引用

页数：8

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