Primary angiitis of the CNS

被引:244
作者
Hajj-Ali, Rula A.
Singhal, Aneesh B. [2 ]
Benseler, Susanne [3 ]
Molloy, Eamonn [4 ]
Calabrese, Leonard H. [1 ]
机构
[1] Cleveland Clin, Dept Rheumat & Immunol Dis, Orthopaed & Rheumatol Inst, Cleveland, OH 44195 USA
[2] Massachusetts Gen Hosp, Dept Neurol, Boston, MA 02114 USA
[3] Univ Toronto, Hosp Sick Children, Div Rheumatol, Dept Paediat, Toronto, ON M5G 1X8, Canada
[4] St Vincents Univ Hosp, Dublin 4, Ireland
关键词
CENTRAL-NERVOUS-SYSTEM; CEREBRAL AMYLOID ANGIOPATHY; GRANULOMATOUS-ANGIITIS; BRAIN BIOPSY; VASCULITIS; ANGIOGRAPHY; MR; CHILDREN; STROKE; ARTERIOPATHY;
D O I
10.1016/S1474-4422(11)70081-3
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Meaningful progress in our understanding and clinical approach to primary angiitis of the CNS (PACNS) has been made in the past three decades. Increased recognition of PACNS and general advances in diagnosis of neurological disorders have led to an aggressive diagnostic approach and a proliferation of case reports providing enriched clinical and pathological descriptions. We have witnessed major advances not only in the diagnosis of PACNS but in the recognition of its mimics. Epidemiological, clinical, neuroradiagnostic, and laboratory findings have enhanced our diagnostic accuracy and recognition of PACNS mimics, however, many challenges to our understanding and management of the disease in children and adults remain.
引用
收藏
页码:561 / 572
页数:12
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